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Coupling Bulk Phase Separation of Disordered Proteins to Membrane Domain Formation in Molecular Simulations on a Bespoke Compute Fabric

Phospholipid membranes surround the cell and its internal organelles, and their multicomponent nature allows the formation of domains that are important in cellular signalling, the immune system, and bacterial infection. Cytoplasmic compartments are also created by the phase separation of intrinsica...

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Detalles Bibliográficos
Autores principales: Shillcock, Julian C., Thomas, David B., Beaumont, Jonathan R., Bragg, Graeme M., Vousden, Mark L., Brown, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779898/
https://www.ncbi.nlm.nih.gov/pubmed/35054543
http://dx.doi.org/10.3390/membranes12010017

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