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Long-Term Outcomes of Chronic Cough Reduction after Laparoscopic Nissen Fundoplication—A Single-Center Study

Background and Objectives: Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal diseases. It affects 20% of the adult population and is the third most common cause of chronic cough in adults. This study describes the results of LNF for the relief of GERD-related cough. M...

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Autores principales: Dowgiałło-Gornowicz, Natalia, Masiewicz, Anna, Kacperczyk, Justyna, Lech, Paweł, Saluk, Sławomir, Osowiecka, Karolina, Michalik, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779940/
https://www.ncbi.nlm.nih.gov/pubmed/35056354
http://dx.doi.org/10.3390/medicina58010047
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author Dowgiałło-Gornowicz, Natalia
Masiewicz, Anna
Kacperczyk, Justyna
Lech, Paweł
Saluk, Sławomir
Osowiecka, Karolina
Michalik, Maciej
author_facet Dowgiałło-Gornowicz, Natalia
Masiewicz, Anna
Kacperczyk, Justyna
Lech, Paweł
Saluk, Sławomir
Osowiecka, Karolina
Michalik, Maciej
author_sort Dowgiałło-Gornowicz, Natalia
collection PubMed
description Background and Objectives: Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal diseases. It affects 20% of the adult population and is the third most common cause of chronic cough in adults. This study describes the results of LNF for the relief of GERD-related cough. Materials and Methods: The prospectively collected data on 135 laparoscopic LNF in our department from 2014 to 2018 were reviewed. During consultations, patients were asked about the frequency of symptoms using the GERD Impact Scale (GERD-IS), their satisfaction and recommendation to others, and their general condition after the procedure. Results: We analyzed 23 of 111 patients (20.7%) reporting chronic cough. The mean age was 47 years (range 27–76 years, ±13.9 years) and the mean follow-up time was 48.3 months (range 22.6–76.3 ± 18.05 months). Most patients reported relief from cough after the surgery (78.3%, p < 0.001). Five patients (22%) reported the recurrence of symptoms after a mean of 10.8 months (6–18 months). Seventeen patients (74%) would undergo the surgery again and 18 patients (78%) would recommend the surgery to their relatives. There was a statistically significant improvement in all symptoms from the GERD-IS (p < 0.05). Conclusions: LNF may play an important role in the management of GERD patients with extraesophageal symptoms. After LNF, most of the operated patients reported complete resolution of chronic cough and would recommend the procedure to their relatives.
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spelling pubmed-87799402022-01-22 Long-Term Outcomes of Chronic Cough Reduction after Laparoscopic Nissen Fundoplication—A Single-Center Study Dowgiałło-Gornowicz, Natalia Masiewicz, Anna Kacperczyk, Justyna Lech, Paweł Saluk, Sławomir Osowiecka, Karolina Michalik, Maciej Medicina (Kaunas) Article Background and Objectives: Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal diseases. It affects 20% of the adult population and is the third most common cause of chronic cough in adults. This study describes the results of LNF for the relief of GERD-related cough. Materials and Methods: The prospectively collected data on 135 laparoscopic LNF in our department from 2014 to 2018 were reviewed. During consultations, patients were asked about the frequency of symptoms using the GERD Impact Scale (GERD-IS), their satisfaction and recommendation to others, and their general condition after the procedure. Results: We analyzed 23 of 111 patients (20.7%) reporting chronic cough. The mean age was 47 years (range 27–76 years, ±13.9 years) and the mean follow-up time was 48.3 months (range 22.6–76.3 ± 18.05 months). Most patients reported relief from cough after the surgery (78.3%, p < 0.001). Five patients (22%) reported the recurrence of symptoms after a mean of 10.8 months (6–18 months). Seventeen patients (74%) would undergo the surgery again and 18 patients (78%) would recommend the surgery to their relatives. There was a statistically significant improvement in all symptoms from the GERD-IS (p < 0.05). Conclusions: LNF may play an important role in the management of GERD patients with extraesophageal symptoms. After LNF, most of the operated patients reported complete resolution of chronic cough and would recommend the procedure to their relatives. MDPI 2021-12-28 /pmc/articles/PMC8779940/ /pubmed/35056354 http://dx.doi.org/10.3390/medicina58010047 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Dowgiałło-Gornowicz, Natalia
Masiewicz, Anna
Kacperczyk, Justyna
Lech, Paweł
Saluk, Sławomir
Osowiecka, Karolina
Michalik, Maciej
Long-Term Outcomes of Chronic Cough Reduction after Laparoscopic Nissen Fundoplication—A Single-Center Study
title Long-Term Outcomes of Chronic Cough Reduction after Laparoscopic Nissen Fundoplication—A Single-Center Study
title_full Long-Term Outcomes of Chronic Cough Reduction after Laparoscopic Nissen Fundoplication—A Single-Center Study
title_fullStr Long-Term Outcomes of Chronic Cough Reduction after Laparoscopic Nissen Fundoplication—A Single-Center Study
title_full_unstemmed Long-Term Outcomes of Chronic Cough Reduction after Laparoscopic Nissen Fundoplication—A Single-Center Study
title_short Long-Term Outcomes of Chronic Cough Reduction after Laparoscopic Nissen Fundoplication—A Single-Center Study
title_sort long-term outcomes of chronic cough reduction after laparoscopic nissen fundoplication—a single-center study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779940/
https://www.ncbi.nlm.nih.gov/pubmed/35056354
http://dx.doi.org/10.3390/medicina58010047
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