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Myocardial Afterload Is a Key Biomechanical Regulator of Atrioventricular Myocyte Differentiation in Zebrafish

Heart valve development is governed by both genetic and biomechanical inputs. Prior work has demonstrated that oscillating shear stress associated with blood flow is required for normal atrioventricular (AV) valve development. Cardiac afterload is defined as the pressure the ventricle must overcome...

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Detalles Bibliográficos
Autores principales: Ahuja, Neha, Ostwald, Paige, Gendernalik, Alex, Guzzolino, Elena, Pitto, Letizia, Bark, David, Garrity, Deborah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779957/
https://www.ncbi.nlm.nih.gov/pubmed/35050232
http://dx.doi.org/10.3390/jcdd9010022

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