Cargando…

Systemic administration of dendrimer N‐acetyl cysteine improves outcomes and survival following cardiac arrest

Cardiac arrest (CA), the sudden cessation of effective cardiac pumping function, is still a major clinical problem with a high rate of early and long‐term mortality. Post‐cardiac arrest syndrome (PCAS) may be related to an early systemic inflammatory response leading to exaggerated and sustained neu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Modi, Hiren R., Wang, Qihong, Olmstead, Sarah J., Khoury, Elizabeth S., Sah, Nirnath, Guo, Yu, Gharibani, Payam, Sharma, Rishi, Kannan, Rangaramanujam M., Kannan, Sujatha, Thakor, Nitish V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780014/ https://www.ncbi.nlm.nih.gov/pubmed/35079634 http://dx.doi.org/10.1002/btm2.10259

Ejemplares similares

Scalable synthesis and validation of PAMAM dendrimer‐N‐acetyl cysteine conjugate for potential translation
por: Sharma, Rishi, et al.
Publicado: (2018)

Dendrimer-mediated delivery of N-acetyl cysteine to microglia in a mouse model of Rett syndrome
por: Nance, Elizabeth, et al.
Publicado: (2017)

Dendrimer-Conjugated Glutamate Carboxypeptidase II Inhibitor Restores Microglial Changes in a Rabbit Model of Cerebral Palsy
por: Sah, Nirnath, et al.
Publicado: (2023)

Correction to: Dendrimer-mediated delivery of N-acetyl cysteine to microglia in a mouse model of Rett syndrome
por: Nance, Elizabeth, et al.
Publicado: (2018)

Dendrimer-Based N-Acetyl Cysteine Maternal Therapy Ameliorates Placental Inflammation via Maintenance of M1/M2 Macrophage Recruitment
por: Liu, Yang, et al.
Publicado: (2022)

Galactosylated hydroxyl‐polyamidoamine dendrimer targets hepatocytes and improves therapeutic outcomes in a severe model of acetaminophen poisoning‐induced liver failure
por: Porterfield, Joshua E., et al.
Publicado: (2023)

Dendrimer size effects on the selective brain tumor targeting in orthotopic tumor models upon systemic administration
por: Liaw, Kevin, et al.
Publicado: (2020)

Targeting Mitochondrial Dysfunction and Oxidative Stress in Activated Microglia using Dendrimer-Based Therapeutics
por: Sharma, Anjali, et al.
Publicado: (2018)

Microglial migration and interactions with dendrimer nanoparticles are altered in the presence of neuroinflammation
por: Zhang, Fan, et al.
Publicado: (2016)

Targeted systemic dendrimer delivery of CSF‐1R inhibitor to tumor‐associated macrophages improves outcomes in orthotopic glioblastoma
por: Liaw, Kevin, et al.
Publicado: (2020)

Systemic dendrimer-drug nanomedicines for long-term treatment of mild-moderate cerebral palsy in a rabbit model
por: Zhang, Zhi, et al.
Publicado: (2020)

Dense hydroxyl polyethylene glycol dendrimer targets activated glia in multiple CNS disorders
por: Sharma, Anjali, et al.
Publicado: (2020)

Dendrimer Brain Uptake and Targeted Therapy for Brain Injury in a Large Animal Model of Hypothermic Circulatory Arrest
por: Mishra, Manoj K., et al.
Publicado: (2014)

Preferential and Increased Uptake of Hydroxyl-Terminated PAMAM Dendrimers by Activated Microglia in Rabbit Brain Mixed Glial Culture
por: Alnasser, Yossef, et al.
Publicado: (2018)

Systemic Dendrimer-Peptide Therapies for Wet Age-Related Macular Degeneration
por: Wu, Tony, et al.
Publicado: (2023)

Dendrimer-conjugated glutaminase inhibitor selectively targets microglial glutaminase in a mouse model of Rett syndrome
por: Khoury, Elizabeth Smith, et al.
Publicado: (2020)

Intranasal Orexin After Cardiac Arrest Leads to Increased Electroencephalographic Gamma Activity and Enhanced Neurologic Recovery in Rats
por: Sherman, David L., et al.
Publicado: (2021)

Intranasal post-cardiac arrest treatment with orexin-A facilitates arousal from coma and ameliorates neuroinflammation
por: Modi, Hiren R., et al.
Publicado: (2017)

Targeted Brain Delivery of Dendrimer-4-Phenylbutyrate Ameliorates Neurological Deficits in a Long-Term ABCD1-Deficient Mouse Model of X-Linked Adrenoleukodystrophy
por: Nemeth, Christina L., et al.
Publicado: (2022)

Dendrimer-2PMPA selectively blocks upregulated microglial GCPII activity and improves cognition in a mouse model of multiple sclerosis
por: Hollinger, Kristen R., et al.
Publicado: (2022)

Dendrimer-Conjugated nSMase2 Inhibitor Reduces Tau Propagation in Mice
por: Tallon, Carolyn, et al.
Publicado: (2022)

Maternal dendrimer-based therapy for inflammation-induced preterm birth and perinatal brain injury
por: Lei, Jun, et al.
Publicado: (2017)

Nanomedicine in cerebral palsy
por: Balakrishnan, Bindu, et al.
Publicado: (2013)

Dendrimers Target the Ischemic Lesion in Rodent and Primate Models of Nonarteritic Anterior Ischemic Optic Neuropathy
por: Guo, Yan, et al.
Publicado: (2016)

Time-Frequency Analysis of Somatosensory Evoked High-Frequency (600 Hz) Oscillations as an Early Indicator of Arousal Recovery after Hypoxic-Ischemic Brain Injury
por: Ou, Ze, et al.
Publicado: (2022)

Engineering clinical translation‐Introduction to Special Issue Dedicated to 2017 Bioengineering and Translational Medicine Conference
por: Kannan, Rangaramanujam M., et al.
Publicado: (2018)

Engineering clinical translation‐Introduction to Special Issue Dedicated to 2017 Bioengineering and Translational Medicine Conference
por: Kannan, Rangaramanujam M., et al.
Publicado: (2018)

Acetylation of PAMAM dendrimers for cellular delivery of siRNA
por: Waite, Carolyn L, et al.
Publicado: (2009)

Neuroprotective effects of a dendrimer-based glutamate carboxypeptidase inhibitor on superoxide dismutase transgenic mice after neonatal hypoxic-ischemic brain injury
por: Cabeza, O. Arteaga, et al.
Publicado: (2020)

DNA Condensation by Partially Acetylated Poly(amido amine) Dendrimers: Effects of Dendrimer Charge Density on Complex Formation
por: Yu, Shi, et al.
Publicado: (2013)

N-Acetyl-Cysteine: Modulating the Cysteine Redox Proteome in Neurodegenerative Diseases
por: Martinez-Banaclocha, Marcos
Publicado: (2022)

Oral administration of N-acetyl cysteine prevents osteoarthritis development and progression in a rat model
por: Kaneko, Yosuke, et al.
Publicado: (2019)

Nanotechnology Approaches for Ocular Drug Delivery
por: Xu, Qingguo, et al.
Publicado: (2013)

N-Acetyl Cysteine as an Adjunct in the Treatment of Tuberculosis
por: Ejigu, Dawit A., et al.
Publicado: (2020)

N-acetyl-L-cysteine and cysteine increase intracellular calcium concentration in human neutrophils
por: Hasan, Md. Ashraful, et al.
Publicado: (2016)

Co-Administration of Metformin and N-Acetyl Cysteine Fails to Improve Clinical Manifestations in PCOS Individual Undergoing ICSI
por: Cheraghi, Ebrahim, et al.
Publicado: (2014)

N-acetyl Cysteine Administration Is Associated With Increased Cerebral Glucose Metabolism in Patients With Multiple Sclerosis: An Exploratory Study
por: Monti, Daniel A., et al.
Publicado: (2020)

Efficacy of N-Acetyl Cysteine in Traumatic Brain Injury
por: Eakin, Katharine, et al.
Publicado: (2014)

A Review on Various Uses of N-Acetyl Cysteine
por: Mokhtari, Vida, et al.
Publicado: (2017)

N-acetyl Cysteine Use in the Treatment of Shock Liver
por: Parvataneni, Swetha, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_t6ehsmtath9g23fbfg0ukhg2mu