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Assessment of Biventricular Myocardial Function with 2-Dimensional Strain and Conventional Echocardiographic Parameters: A Comparative Analysis in Healthy Infants and Patients with Severe and Critical Pulmonary Stenosis

Our aim was to compare the global longitudinal and regional biventricular strain between infants with severe and critical pulmonary stenosis (PS), and controls; to compare pre- and post-procedural strain values in infants with severe and critical PS; and to assess the correlations between echocardio...

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Autores principales: Gozar, Liliana, Iancu, Mihaela, Gozar, Horea, Sglimbea, Anca, Cerghit Paler, Andreea, Gabor-Miklosi, Dorottya, Toganel, Rodica, Făgărășan, Amalia, Iurian, Diana Ramona, Toma, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780169/
https://www.ncbi.nlm.nih.gov/pubmed/35055372
http://dx.doi.org/10.3390/jpm12010057
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author Gozar, Liliana
Iancu, Mihaela
Gozar, Horea
Sglimbea, Anca
Cerghit Paler, Andreea
Gabor-Miklosi, Dorottya
Toganel, Rodica
Făgărășan, Amalia
Iurian, Diana Ramona
Toma, Daniela
author_facet Gozar, Liliana
Iancu, Mihaela
Gozar, Horea
Sglimbea, Anca
Cerghit Paler, Andreea
Gabor-Miklosi, Dorottya
Toganel, Rodica
Făgărășan, Amalia
Iurian, Diana Ramona
Toma, Daniela
author_sort Gozar, Liliana
collection PubMed
description Our aim was to compare the global longitudinal and regional biventricular strain between infants with severe and critical pulmonary stenosis (PS), and controls; to compare pre- and post-procedural strain values in infants with severe and critical PS; and to assess the correlations between echocardiographic strain and conventional parameters. We conducted a retrospective single-center study. The comparisons of echocardiographic variables were performed using separate linear mixed models. The overall mean right ventricle (RV) regional strains measured before intervention in PS patients was significantly different when compared to the control group (p = 0.0324). We found a significant change in the left ventricle, RV, and inter-ventricular septum strain (IVS) values from basal to apical location (p < 0.05). IVS strain values showed a higher decrease in mean strain values from basal to apical in PS patients. There was no significant difference in means of baseline and post-interventional strain values in PS patients (p > 0.05). Following the strain analysis in patients with PS, we obtained statistically significant changes in the RV global-4-chamber longitudinal strain (RV4C). The RV4C, which quantifies the longitudinal strain to the entire RV, can be used in current clinical practice for the evaluation of RV function in infants with severe and critical PS. The longitudinal and segmental strain capture the pathological changes in the IVS, modifications that cannot be highlighted through a classical echocardiographic evaluation.
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spelling pubmed-87801692022-01-22 Assessment of Biventricular Myocardial Function with 2-Dimensional Strain and Conventional Echocardiographic Parameters: A Comparative Analysis in Healthy Infants and Patients with Severe and Critical Pulmonary Stenosis Gozar, Liliana Iancu, Mihaela Gozar, Horea Sglimbea, Anca Cerghit Paler, Andreea Gabor-Miklosi, Dorottya Toganel, Rodica Făgărășan, Amalia Iurian, Diana Ramona Toma, Daniela J Pers Med Article Our aim was to compare the global longitudinal and regional biventricular strain between infants with severe and critical pulmonary stenosis (PS), and controls; to compare pre- and post-procedural strain values in infants with severe and critical PS; and to assess the correlations between echocardiographic strain and conventional parameters. We conducted a retrospective single-center study. The comparisons of echocardiographic variables were performed using separate linear mixed models. The overall mean right ventricle (RV) regional strains measured before intervention in PS patients was significantly different when compared to the control group (p = 0.0324). We found a significant change in the left ventricle, RV, and inter-ventricular septum strain (IVS) values from basal to apical location (p < 0.05). IVS strain values showed a higher decrease in mean strain values from basal to apical in PS patients. There was no significant difference in means of baseline and post-interventional strain values in PS patients (p > 0.05). Following the strain analysis in patients with PS, we obtained statistically significant changes in the RV global-4-chamber longitudinal strain (RV4C). The RV4C, which quantifies the longitudinal strain to the entire RV, can be used in current clinical practice for the evaluation of RV function in infants with severe and critical PS. The longitudinal and segmental strain capture the pathological changes in the IVS, modifications that cannot be highlighted through a classical echocardiographic evaluation. MDPI 2022-01-06 /pmc/articles/PMC8780169/ /pubmed/35055372 http://dx.doi.org/10.3390/jpm12010057 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gozar, Liliana
Iancu, Mihaela
Gozar, Horea
Sglimbea, Anca
Cerghit Paler, Andreea
Gabor-Miklosi, Dorottya
Toganel, Rodica
Făgărășan, Amalia
Iurian, Diana Ramona
Toma, Daniela
Assessment of Biventricular Myocardial Function with 2-Dimensional Strain and Conventional Echocardiographic Parameters: A Comparative Analysis in Healthy Infants and Patients with Severe and Critical Pulmonary Stenosis
title Assessment of Biventricular Myocardial Function with 2-Dimensional Strain and Conventional Echocardiographic Parameters: A Comparative Analysis in Healthy Infants and Patients with Severe and Critical Pulmonary Stenosis
title_full Assessment of Biventricular Myocardial Function with 2-Dimensional Strain and Conventional Echocardiographic Parameters: A Comparative Analysis in Healthy Infants and Patients with Severe and Critical Pulmonary Stenosis
title_fullStr Assessment of Biventricular Myocardial Function with 2-Dimensional Strain and Conventional Echocardiographic Parameters: A Comparative Analysis in Healthy Infants and Patients with Severe and Critical Pulmonary Stenosis
title_full_unstemmed Assessment of Biventricular Myocardial Function with 2-Dimensional Strain and Conventional Echocardiographic Parameters: A Comparative Analysis in Healthy Infants and Patients with Severe and Critical Pulmonary Stenosis
title_short Assessment of Biventricular Myocardial Function with 2-Dimensional Strain and Conventional Echocardiographic Parameters: A Comparative Analysis in Healthy Infants and Patients with Severe and Critical Pulmonary Stenosis
title_sort assessment of biventricular myocardial function with 2-dimensional strain and conventional echocardiographic parameters: a comparative analysis in healthy infants and patients with severe and critical pulmonary stenosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780169/
https://www.ncbi.nlm.nih.gov/pubmed/35055372
http://dx.doi.org/10.3390/jpm12010057
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