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Lipid Specific Membrane Interaction of Aptamers and Cytotoxicity

We aim to discover diagnostic tools to detect phosphatidylserine (PS) externalization on apoptotic cell surface using PS binding aptamers, AAAGAC and TAAAGA, and hence to understand chemotherapy drug efficacy when inducing apoptosis into cancer cells. The entropic fragment-based approach designed ap...

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Detalles Bibliográficos
Autores principales:	Ashrafuzzaman, Md., AlMansour, Hanouf A. M., AlOtaibi, Maha A. S., Khan, Zahid, Shaik, Gouse M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780203/ https://www.ncbi.nlm.nih.gov/pubmed/35054563 http://dx.doi.org/10.3390/membranes12010037

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