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ICBrainDB: An Integrated Database for Finding Associations between Genetic Factors and EEG Markers of Depressive Disorders

In this study, we collected and systemized diverse information related to depressive and anxiety disorders as the first step on the way to investigate the associations between molecular genetics, electrophysiological, behavioral, and psychological characteristics of people. Keeping that in mind, we...

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Autores principales: Ivanov, Roman, Kazantsev, Fedor, Zavarzin, Evgeny, Klimenko, Alexandra, Milakhina, Natalya, Matushkin, Yury G., Savostyanov, Alexander, Lashin, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780210/
https://www.ncbi.nlm.nih.gov/pubmed/35055368
http://dx.doi.org/10.3390/jpm12010053
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author Ivanov, Roman
Kazantsev, Fedor
Zavarzin, Evgeny
Klimenko, Alexandra
Milakhina, Natalya
Matushkin, Yury G.
Savostyanov, Alexander
Lashin, Sergey
author_facet Ivanov, Roman
Kazantsev, Fedor
Zavarzin, Evgeny
Klimenko, Alexandra
Milakhina, Natalya
Matushkin, Yury G.
Savostyanov, Alexander
Lashin, Sergey
author_sort Ivanov, Roman
collection PubMed
description In this study, we collected and systemized diverse information related to depressive and anxiety disorders as the first step on the way to investigate the associations between molecular genetics, electrophysiological, behavioral, and psychological characteristics of people. Keeping that in mind, we developed an internet resource including a database and tools for primary presentation of the collected data of genetic factors, the results of electroencephalography (EEG) tests, and psychological questionnaires. The sample of our study was 1010 people from different regions of Russia. We created the integrated ICBrainDB database that enables users to easily access, download, and further process information about individual behavioral characteristics and psychophysiological responses along with inherited trait data. The data obtained can be useful in training neural networks and in machine learning construction processes in Big Data analysis. We believe that the existence of such a resource will play an important role in the further search for associations of genetic factors and EEG markers of depression.
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spelling pubmed-87802102022-01-22 ICBrainDB: An Integrated Database for Finding Associations between Genetic Factors and EEG Markers of Depressive Disorders Ivanov, Roman Kazantsev, Fedor Zavarzin, Evgeny Klimenko, Alexandra Milakhina, Natalya Matushkin, Yury G. Savostyanov, Alexander Lashin, Sergey J Pers Med Article In this study, we collected and systemized diverse information related to depressive and anxiety disorders as the first step on the way to investigate the associations between molecular genetics, electrophysiological, behavioral, and psychological characteristics of people. Keeping that in mind, we developed an internet resource including a database and tools for primary presentation of the collected data of genetic factors, the results of electroencephalography (EEG) tests, and psychological questionnaires. The sample of our study was 1010 people from different regions of Russia. We created the integrated ICBrainDB database that enables users to easily access, download, and further process information about individual behavioral characteristics and psychophysiological responses along with inherited trait data. The data obtained can be useful in training neural networks and in machine learning construction processes in Big Data analysis. We believe that the existence of such a resource will play an important role in the further search for associations of genetic factors and EEG markers of depression. MDPI 2022-01-05 /pmc/articles/PMC8780210/ /pubmed/35055368 http://dx.doi.org/10.3390/jpm12010053 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ivanov, Roman
Kazantsev, Fedor
Zavarzin, Evgeny
Klimenko, Alexandra
Milakhina, Natalya
Matushkin, Yury G.
Savostyanov, Alexander
Lashin, Sergey
ICBrainDB: An Integrated Database for Finding Associations between Genetic Factors and EEG Markers of Depressive Disorders
title ICBrainDB: An Integrated Database for Finding Associations between Genetic Factors and EEG Markers of Depressive Disorders
title_full ICBrainDB: An Integrated Database for Finding Associations between Genetic Factors and EEG Markers of Depressive Disorders
title_fullStr ICBrainDB: An Integrated Database for Finding Associations between Genetic Factors and EEG Markers of Depressive Disorders
title_full_unstemmed ICBrainDB: An Integrated Database for Finding Associations between Genetic Factors and EEG Markers of Depressive Disorders
title_short ICBrainDB: An Integrated Database for Finding Associations between Genetic Factors and EEG Markers of Depressive Disorders
title_sort icbraindb: an integrated database for finding associations between genetic factors and eeg markers of depressive disorders
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780210/
https://www.ncbi.nlm.nih.gov/pubmed/35055368
http://dx.doi.org/10.3390/jpm12010053
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