Cargando…

Dendritic cell-mediated chronic low-grade inflammation is regulated by the RAGE-TLR4-PKCβ(1) signaling pathway in diabetic atherosclerosis

BACKGROUND: The unique mechanism of diabetic atherosclerosis has been a central research focus. Previous literature has reported that the inflammatory response mediated by dendritic cells (DCs) plays a vital role in the progression of atherosclerosis. The objective of the study was to explore the ro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Liding, Li, Ya, Xu, Tian, Lv, Qingbo, Bi, Xukun, Liu, Xianglan, Fu, Guosheng, Zou, Yunzeng, Ge, Junbo, Chen, Zhaoyang, Zhang, Wenbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780245/ https://www.ncbi.nlm.nih.gov/pubmed/35062863 http://dx.doi.org/10.1186/s10020-022-00431-6

Ejemplares similares

Metoprolol and bisoprolol ameliorate hypertrophy of neonatal rat cardiomyocytes induced by high glucose via the PKC/NF-κB/c-fos signaling pathway
por: Wang, Min, et al.
Publicado: (2020)

Metoprolol and bisoprolol ameliorate hypertrophy of neonatal rat cardiomyocytes induced by high glucose via the PKC/NF-κB/c-fos signaling pathway
por: Wang, Min, et al.
Publicado: (2022)

Atorvastatin Represses the Angiotensin 2-Induced Oxidative Stress and Inflammatory Response in Dendritic Cells via the PI3K/Akt/Nrf 2 Pathway
por: Ma, Yuanji, et al.
Publicado: (2014)

Variability in blood lipids affects the neutrophil to lymphocyte ratio in patients undergoing elective percutaneous coronary intervention: a retrospective study
por: Zhao, Liding, et al.
Publicado: (2020)

Gensini score values for predicting periprocedural myocardial infarction: An observational study analysis
por: Wang, Yao, et al.
Publicado: (2022)

Impact of increased inflammation biomarkers on periprocedural myocardial infarction in patients undergoing elective percutaneous coronary intervention: a cohort study
por: Zhao, Liding, et al.
Publicado: (2020)

Rosuvastatin Reverses Hypertension-Induced Changes in the Aorta Structure and Endothelium-Dependent Relaxation in Rats Through Suppression of Apoptosis and Inflammation
por: Lv, Qingbo, et al.
Publicado: (2020)

Dicarbonyl Stress and Atherosclerosis: Is It All RAGE?
por: Muniyappa, Ranganath, et al.
Publicado: (2014)

Admission electrolyte and osmotic pressure levels are associated with the incidence of contrast-associated acute kidney injury
por: Lv, Qingbo, et al.
Publicado: (2022)

HMGB1 enhances mechanical stress-induced cardiomyocyte hypertrophy in vitro via the RAGE/ERK1/2 signaling pathway
por: Zhang, Lei, et al.
Publicado: (2019)

iPLA(2)β Contributes to ER Stress-Induced Apoptosis during Myocardial Ischemia/Reperfusion Injury
por: Jin, Tingting, et al.
Publicado: (2021)

Primary prevention of myocardial infarction: aspirin is not as useful as it seems
por: Luan, Yi, et al.
Publicado: (2020)

microRNA-181a represses ox-LDL-stimulated inflammatory response in dendritic cell by targeting c-Fos
por: Wu, Chaoneng, et al.
Publicado: (2012)

Correlation Analysis of CML, sRAGE, and esRAGE and the Measure of Atherosclerosis of Coronary Heart Disease
por: Liu, Wenjun, et al.
Publicado: (2022)

Exosomes derived from mature dendritic cells increase endothelial inflammation and atherosclerosis via membrane TNF‐α mediated NF‐κB pathway
por: Gao, Wei, et al.
Publicado: (2016)

Advanced Glycation End Product (AGE)-AGE Receptor (RAGE) System Upregulated Connexin43 Expression in Rat Cardiomyocytes via PKC and Erk MAPK Pathways
por: Yu, Lu, et al.
Publicado: (2013)

Retracted: Correlation Analysis of CML, sRAGE, and esRAGE and the Measure of Atherosclerosis of Coronary Heart Disease
por: Intelligence and Neuroscience, Computational
Publicado: (2023)

Prognostic significance of troponin increment after percutaneous coronary intervention: A retrospective study
por: Li, Ya, et al.
Publicado: (2022)

Hyperlipidemia inhibits the protective effect of lisinopril after myocardial infarction via activation of dendritic cells
por: Ma, Yuanji, et al.
Publicado: (2020)

Probucol Protects Against Atherosclerosis Through Lipid-lowering and Suppressing Immune Maturation of CD11c(+) Dendritic Cells in STZ-induced Diabetic LDLR(−/−) Mice
por: Zhu, Hong, et al.
Publicado: (2015)

High glucose induces upregulation of scavenger receptors and promotes maturation of dendritic cells
por: Lu, Hao, et al.
Publicado: (2013)

sRAGE alleviates neutrophilic asthma by blocking HMGB1/RAGE signalling in airway dendritic cells
por: Zhang, Fang, et al.
Publicado: (2017)

PKCδ regulates the vascular biology in diabetic atherosclerosis
por: Qin, Peiliang, et al.
Publicado: (2023)

The Essential Role of Pin1 via NF-κB Signaling in Vascular Inflammation and Atherosclerosis in ApoE(−/−) Mice
por: Liu, Ming, et al.
Publicado: (2017)

AKF-PD alleviates diabetic nephropathy via blocking the RAGE/AGEs/NOX and PKC/NOX Pathways
por: Qin, Jiao, et al.
Publicado: (2019)

The helminth product, ES-62 modulates dendritic cell responses by inducing the selective autophagolysosomal degradation of TLR-transducers, as exemplified by PKCδ
por: Eason, Russell J., et al.
Publicado: (2016)

The Role of TLR2, TLR4, and TLR9 in the Pathogenesis of Atherosclerosis
por: Roshan, Mohsin H. K., et al.
Publicado: (2016)

RAGE Mediates Accelerated Diabetic Vein Graft Atherosclerosis Induced by Combined Mechanical Stress and AGEs via Synergistic ERK Activation
por: Li, Yuhuang, et al.
Publicado: (2012)

Diabetes Exacerbates Infection via Hyperinflammation by Signaling through TLR4 and RAGE
por: Nielsen, Travis B., et al.
Publicado: (2017)

Mitochondrial Transcription Factor A, an Endogenous Danger Signal, Promotes TNFα Release via RAGE- and TLR9-Responsive Plasmacytoid Dendritic Cells
por: Julian, Mark W., et al.
Publicado: (2013)

Subcutaneous injection of dendritic cells aggravates atherosclerosis in ApoE-knockout mice by activation of TLR4
por: Ye, Zhishuai, et al.
Publicado: (2017)

Granulocyte Colony-Stimulating Factor Promotes Atherosclerosis in High-Fat Diet Rabbits
por: Hu, Zhaohui, et al.
Publicado: (2013)

Naoxintong Retards Atherosclerosis by Inhibiting Foam Cell Formation through Activating PPARα Pathway
por: Wang, Zeng, et al.
Publicado: (2018)

PKCε inhibition prevents ischemia‑induced dendritic spine impairment in cultured primary neurons
por: Ge, Chenjie, et al.
Publicado: (2023)

Infection and atherosclerosis: TLR-dependent pathways
por: Li, Bowei, et al.
Publicado: (2020)

Receptor for Advanced Glycation End Products (RAGE) Deficiency Attenuates the Development of Atherosclerosis in Diabetes
por: Soro-Paavonen, Aino, et al.
Publicado: (2008)

Biomimetic and NOS‐Responsive Nanomotor Deeply Delivery a Combination of MSC‐EV and Mitochondrial ROS Scavenger and Promote Heart Repair and Regeneration
por: Zhang, Ning, et al.
Publicado: (2023)

Dendritic cells derived exosomes migration to spleen and induction of inflammation are regulated by CCR7
por: Wei, Gao, et al.
Publicado: (2017)

Assessment of EN-RAGE, sRAGE and EN-RAGE/sRAGE as potential biomarkers in patients with autoimmune hepatitis
por: Wu, Rui, et al.
Publicado: (2020)

Changes of dendritic cells and fractalkine in type 2 diabetic patients with unstable angina pectoris: a preliminary report
por: Yao, Kang, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_b38o5fa7miugc4mlblbbnii60d