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Improved Neomycin Sulfate Potency in Streptomyces fradiae Using Atmospheric and Room Temperature Plasma (ARTP) Mutagenesis and Fermentation Medium Optimization

To improve the screening efficiency of high-yield neomycin sulfate (NM) Streptomyces fradiae strains after mutagenesis, a high-throughput screening method using streptomycin resistance prescreening (8 μg/mL) and a 24-deep well plates/microplate reader (trypan blue spectrophotometry) rescreening stra...

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Detalles Bibliográficos
Autores principales: Yu, Fei, Zhang, Min, Sun, Junfeng, Wang, Fang, Li, Xiangfei, Liu, Yan, Wang, Zhou, Zhao, Xinrui, Li, Jianghua, Chen, Jian, Du, Guocheng, Xue, Zhenglian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780280/
https://www.ncbi.nlm.nih.gov/pubmed/35056543
http://dx.doi.org/10.3390/microorganisms10010094