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Polymer-Based Nanofiber–Nanoparticle Hybrids and Their Medical Applications

The search for higher-quality nanomaterials for medicinal applications continues. There are similarities between electrospun fibers and natural tissues. This property has enabled electrospun fibers to make significant progress in medical applications. However, electrospun fibers are limited to tissu...

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Autores principales: Zhang, Mingxin, Song, Wenliang, Tang, Yunxin, Xu, Xizi, Huang, Yingning, Yu, Dengguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780324/
https://www.ncbi.nlm.nih.gov/pubmed/35054758
http://dx.doi.org/10.3390/polym14020351
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author Zhang, Mingxin
Song, Wenliang
Tang, Yunxin
Xu, Xizi
Huang, Yingning
Yu, Dengguang
author_facet Zhang, Mingxin
Song, Wenliang
Tang, Yunxin
Xu, Xizi
Huang, Yingning
Yu, Dengguang
author_sort Zhang, Mingxin
collection PubMed
description The search for higher-quality nanomaterials for medicinal applications continues. There are similarities between electrospun fibers and natural tissues. This property has enabled electrospun fibers to make significant progress in medical applications. However, electrospun fibers are limited to tissue scaffolding applications. When nanoparticles and nanofibers are combined, the composite material can perform more functions, such as photothermal, magnetic response, biosensing, antibacterial, drug delivery and biosensing. To prepare nanofiber and nanoparticle hybrids (NNHs), there are two primary ways. The electrospinning technology was used to produce NNHs in a single step. An alternate way is to use a self-assembly technique to create nanoparticles in fibers. This paper describes the creation of NNHs from routinely used biocompatible polymer composites. Single-step procedures and self-assembly methodologies are used to discuss the preparation of NNHs. It combines recent research discoveries to focus on the application of NNHs in drug release, antibacterial, and tissue engineering in the last two years.
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spelling pubmed-87803242022-01-22 Polymer-Based Nanofiber–Nanoparticle Hybrids and Their Medical Applications Zhang, Mingxin Song, Wenliang Tang, Yunxin Xu, Xizi Huang, Yingning Yu, Dengguang Polymers (Basel) Review The search for higher-quality nanomaterials for medicinal applications continues. There are similarities between electrospun fibers and natural tissues. This property has enabled electrospun fibers to make significant progress in medical applications. However, electrospun fibers are limited to tissue scaffolding applications. When nanoparticles and nanofibers are combined, the composite material can perform more functions, such as photothermal, magnetic response, biosensing, antibacterial, drug delivery and biosensing. To prepare nanofiber and nanoparticle hybrids (NNHs), there are two primary ways. The electrospinning technology was used to produce NNHs in a single step. An alternate way is to use a self-assembly technique to create nanoparticles in fibers. This paper describes the creation of NNHs from routinely used biocompatible polymer composites. Single-step procedures and self-assembly methodologies are used to discuss the preparation of NNHs. It combines recent research discoveries to focus on the application of NNHs in drug release, antibacterial, and tissue engineering in the last two years. MDPI 2022-01-17 /pmc/articles/PMC8780324/ /pubmed/35054758 http://dx.doi.org/10.3390/polym14020351 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zhang, Mingxin
Song, Wenliang
Tang, Yunxin
Xu, Xizi
Huang, Yingning
Yu, Dengguang
Polymer-Based Nanofiber–Nanoparticle Hybrids and Their Medical Applications
title Polymer-Based Nanofiber–Nanoparticle Hybrids and Their Medical Applications
title_full Polymer-Based Nanofiber–Nanoparticle Hybrids and Their Medical Applications
title_fullStr Polymer-Based Nanofiber–Nanoparticle Hybrids and Their Medical Applications
title_full_unstemmed Polymer-Based Nanofiber–Nanoparticle Hybrids and Their Medical Applications
title_short Polymer-Based Nanofiber–Nanoparticle Hybrids and Their Medical Applications
title_sort polymer-based nanofiber–nanoparticle hybrids and their medical applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780324/
https://www.ncbi.nlm.nih.gov/pubmed/35054758
http://dx.doi.org/10.3390/polym14020351
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