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Polymer-Based Nanofiber–Nanoparticle Hybrids and Their Medical Applications
The search for higher-quality nanomaterials for medicinal applications continues. There are similarities between electrospun fibers and natural tissues. This property has enabled electrospun fibers to make significant progress in medical applications. However, electrospun fibers are limited to tissu...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780324/ https://www.ncbi.nlm.nih.gov/pubmed/35054758 http://dx.doi.org/10.3390/polym14020351 |
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author | Zhang, Mingxin Song, Wenliang Tang, Yunxin Xu, Xizi Huang, Yingning Yu, Dengguang |
author_facet | Zhang, Mingxin Song, Wenliang Tang, Yunxin Xu, Xizi Huang, Yingning Yu, Dengguang |
author_sort | Zhang, Mingxin |
collection | PubMed |
description | The search for higher-quality nanomaterials for medicinal applications continues. There are similarities between electrospun fibers and natural tissues. This property has enabled electrospun fibers to make significant progress in medical applications. However, electrospun fibers are limited to tissue scaffolding applications. When nanoparticles and nanofibers are combined, the composite material can perform more functions, such as photothermal, magnetic response, biosensing, antibacterial, drug delivery and biosensing. To prepare nanofiber and nanoparticle hybrids (NNHs), there are two primary ways. The electrospinning technology was used to produce NNHs in a single step. An alternate way is to use a self-assembly technique to create nanoparticles in fibers. This paper describes the creation of NNHs from routinely used biocompatible polymer composites. Single-step procedures and self-assembly methodologies are used to discuss the preparation of NNHs. It combines recent research discoveries to focus on the application of NNHs in drug release, antibacterial, and tissue engineering in the last two years. |
format | Online Article Text |
id | pubmed-8780324 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87803242022-01-22 Polymer-Based Nanofiber–Nanoparticle Hybrids and Their Medical Applications Zhang, Mingxin Song, Wenliang Tang, Yunxin Xu, Xizi Huang, Yingning Yu, Dengguang Polymers (Basel) Review The search for higher-quality nanomaterials for medicinal applications continues. There are similarities between electrospun fibers and natural tissues. This property has enabled electrospun fibers to make significant progress in medical applications. However, electrospun fibers are limited to tissue scaffolding applications. When nanoparticles and nanofibers are combined, the composite material can perform more functions, such as photothermal, magnetic response, biosensing, antibacterial, drug delivery and biosensing. To prepare nanofiber and nanoparticle hybrids (NNHs), there are two primary ways. The electrospinning technology was used to produce NNHs in a single step. An alternate way is to use a self-assembly technique to create nanoparticles in fibers. This paper describes the creation of NNHs from routinely used biocompatible polymer composites. Single-step procedures and self-assembly methodologies are used to discuss the preparation of NNHs. It combines recent research discoveries to focus on the application of NNHs in drug release, antibacterial, and tissue engineering in the last two years. MDPI 2022-01-17 /pmc/articles/PMC8780324/ /pubmed/35054758 http://dx.doi.org/10.3390/polym14020351 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Zhang, Mingxin Song, Wenliang Tang, Yunxin Xu, Xizi Huang, Yingning Yu, Dengguang Polymer-Based Nanofiber–Nanoparticle Hybrids and Their Medical Applications |
title | Polymer-Based Nanofiber–Nanoparticle Hybrids and Their Medical Applications |
title_full | Polymer-Based Nanofiber–Nanoparticle Hybrids and Their Medical Applications |
title_fullStr | Polymer-Based Nanofiber–Nanoparticle Hybrids and Their Medical Applications |
title_full_unstemmed | Polymer-Based Nanofiber–Nanoparticle Hybrids and Their Medical Applications |
title_short | Polymer-Based Nanofiber–Nanoparticle Hybrids and Their Medical Applications |
title_sort | polymer-based nanofiber–nanoparticle hybrids and their medical applications |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780324/ https://www.ncbi.nlm.nih.gov/pubmed/35054758 http://dx.doi.org/10.3390/polym14020351 |
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