Cargando…

SYNCRIP Modulates the Epithelial-Mesenchymal Transition in Hepatocytes and HCC Cells

Heterogeneous nuclear ribonucleoproteins (hnRNPs) control gene expression by acting at multiple levels and are often deregulated in epithelial tumors; however, their roles in the fine regulation of cellular reprogramming, specifically in epithelial–mesenchymal transition (EMT), remain largely unknow...

Descripción completa

Detalles Bibliográficos
Autores principales:	Riccioni, Veronica, Trionfetti, Flavia, Montaldo, Claudia, Garbo, Sabrina, Marocco, Francesco, Battistelli, Cecilia, Marchetti, Alessandra, Strippoli, Raffaele, Amicone, Laura, Cicchini, Carla, Tripodi, Marco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780347/ https://www.ncbi.nlm.nih.gov/pubmed/35055098 http://dx.doi.org/10.3390/ijms23020913

Ejemplares similares

YAP integrates the regulatory Snail/HNF4α circuitry controlling epithelial/hepatocyte differentiation
por: Noce, Valeria, et al.
Publicado: (2019)

Modulating the Substrate Stiffness to Manipulate Differentiation of Resident Liver Stem Cells and to Improve the Differentiation State of Hepatocytes
por: Cozzolino, Angela Maria, et al.
Publicado: (2016)

TGFβ Impairs HNF1α Functional Activity in Epithelial-to-Mesenchymal Transition Interfering With the Recruitment of CBP/p300 Acetyltransferases
por: Bisceglia, Francesca, et al.
Publicado: (2019)

Molecular Mechanisms Underlying Peritoneal EMT and Fibrosis
por: Strippoli, Raffaele, et al.
Publicado: (2016)

Molecular mechanisms controlling the phenotype and the EMT/MET dynamics of hepatocyte
por: Cicchini, Carla, et al.
Publicado: (2015)

Extracellular signal-Regulated Kinase 5 (ERK5) is required for the Yes-associated protein (YAP) co-transcriptional activity
por: Ippolito, Francesca, et al.
Publicado: (2023)

Functional Roles and Therapeutic Applications of Exosomes in Hepatocellular Carcinoma
por: Santangelo, Laura, et al.
Publicado: (2017)

A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets
por: Hobor, Fruzsina, et al.
Publicado: (2018)

Restoration of WT1/miR-769-5p axis by HDAC1 inhibition promotes MMT reversal in mesenchymal-like mesothelial cells
por: Bontempi, Giulio, et al.
Publicado: (2022)

Mechanisms of Peritoneal Fibrosis: Focus on Immune Cells–Peritoneal Stroma Interactions
por: Terri, Michela, et al.
Publicado: (2021)

A novel RNA-based approach to counteract EMT
por: Garbo, Sabrina, et al.
Publicado: (2021)

lncRNA HOTAIR functions and therapeutic perspectives
por: Garbo, Sabrina, et al.
Publicado: (2022)

The lncRNA HOTAIR transcription is controlled by HNF4α-induced chromatin topology modulation
por: Battistelli, Cecilia, et al.
Publicado: (2018)

Targeting of polycombs to DNA in EMT
por: Battistelli, Cecilia, et al.
Publicado: (2017)

Exosome-Associated circRNAs as Key Regulators of EMT in Cancer
por: Amicone, Laura, et al.
Publicado: (2022)

The lncRNA HOTAIR: a pleiotropic regulator of epithelial cell plasticity
por: Amicone, Laura, et al.
Publicado: (2023)

TGFbeta Induces Binucleation/Polyploidization in Hepatocytes through a Src-Dependent Cytokinesis Failure
por: De Santis Puzzonia, Marco, et al.
Publicado: (2016)

Next RNA Therapeutics: The Mine of Non-Coding
por: Garbo, Sabrina, et al.
Publicado: (2022)

The Snail repressor recruits EZH2 to specific genomic sites through the enrollment of the lncRNA HOTAIR in epithelial-to-mesenchymal transition
por: Battistelli, C, et al.
Publicado: (2017)

Pleural Mesothelial Cells Modulate the Inflammatory/Profibrotic Response During SARS-CoV-2 Infection
por: Matusali, Giulia, et al.
Publicado: (2021)

MyoD-Induced Trans-Differentiation: A Paradigm for Dissecting the Molecular Mechanisms of Cell Commitment, Differentiation and Reprogramming
por: Battistelli, Cecilia, et al.
Publicado: (2022)

Nanomedicine for autophagy modulation in cancer therapy: a clinical perspective
por: López-Méndez, Tania B., et al.
Publicado: (2023)

Correction to: Nanomedicine for autophagy modulation in cancer therapy: a clinical perspective
por: López-Méndez, Tania B., et al.
Publicado: (2023)

Epigenetic Regulation in Hepatocellular Carcinoma Requires Long Noncoding RNAs
por: Amicone, Laura, et al.
Publicado: (2015)

Exposure to b-LED Light While Exerting Antimicrobial Activity on Gram-Negative and -Positive Bacteria Promotes Transient EMT-like Changes and Growth Arrest in Keratinocytes
por: Terri, Michela, et al.
Publicado: (2022)

SYNCRIP, a new player in pri-let-7a processing
por: Chen, Ying, et al.
Publicado: (2020)

Autophagy and the Lysosomal System in Cancer
por: Kumar, Suresh, et al.
Publicado: (2021)

The lncRNA H19 positively affects the tumorigenic properties of glioblastoma cells and contributes to NKD1 repression through the recruitment of EZH2 on its promoter
por: Fazi, Barbara, et al.
Publicado: (2018)

RNA-binding protein syncrip regulates starvation-induced hyperactivity in adult Drosophila
por: Chi, Wanhao, et al.
Publicado: (2021)

Cell-based assay for the detection of chemically induced cellular stress by immortalized untransformed transgenic hepatocytes
por: Sacco, Maria Grazia, et al.
Publicado: (2004)

Editorial: Molecular Mechanisms and New Therapeutic Targets in Epithelial to Mesenchymal Transition (EMT) and Fibrosis
por: Battistelli, Cecilia, et al.
Publicado: (2020)

Editorial: Molecular mechanisms and new therapeutic targets in epithelial to mesenchymal transition (EMT) and fibrosis, volume II
por: Battistelli, Cecilia, et al.
Publicado: (2022)

SYNCRIP controls miR-137 and striatal learning in animal models of methamphetamine abstinence
por: Kim, Baeksun, et al.
Publicado: (2022)

RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells
por: Herrejon Chavez, Florisela, et al.
Publicado: (2023)

HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal
por: Rossi, Lucia, et al.
Publicado: (2018)

Loss of SYNCRIP unleashes APOBEC-driven mutagenesis, tumor heterogeneity, and AR-targeted therapy resistance in prostate cancer
por: Li, Xiaoling, et al.
Publicado: (2023)

Editorial: New Approaches to Tackle EMT and Fibrosis: From Epigenetics to Nanotechnology
por: Battistelli, Cecilia, et al.
Publicado: (2021)

Syncrip/hnRNP Q influences synaptic transmission and regulates BMP signaling at the Drosophila neuromuscular synapse
por: Halstead, James M., et al.
Publicado: (2014)

Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells
por: Vu, Ly P., et al.
Publicado: (2017)

SMO Inhibition Modulates Cellular Plasticity and Invasiveness in Colorectal Cancer
por: Magistri, Paolo, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_t2d5nv9htcg6sctual91ss3p07