Cargando…
How to Explore an Endocrine Cause of Hypertension
Hypertension (HTN) is the most frequent modifiable risk factor in the world, affecting almost 30 to 40% of the adult population in the world. Among hypertensive patients, 10 to 15% have so-called “secondary” HTN, which means HTN due to an identified cause. The most frequent secondary causes of HTN a...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780426/ https://www.ncbi.nlm.nih.gov/pubmed/35054115 http://dx.doi.org/10.3390/jcm11020420 |
_version_ | 1784637834715463680 |
---|---|
author | de Freminville, Jean-Baptiste Amar, Laurence |
author_facet | de Freminville, Jean-Baptiste Amar, Laurence |
author_sort | de Freminville, Jean-Baptiste |
collection | PubMed |
description | Hypertension (HTN) is the most frequent modifiable risk factor in the world, affecting almost 30 to 40% of the adult population in the world. Among hypertensive patients, 10 to 15% have so-called “secondary” HTN, which means HTN due to an identified cause. The most frequent secondary causes of HTN are renal arteries abnormalities (renovascular HTN), kidney disease, and endocrine HTN, which are primarily due to adrenal causes. Knowing how to detect and explore endocrine causes of hypertension is particularly interesting because some causes have a cure or a specific treatment available. Moreover, the delayed diagnosis of secondary HTN is a major cause of uncontrolled blood pressure. Therefore, screening and exploration of patients at risk for secondary HTN should be a serious concern for every physician seeing patients with HTN. Regarding endocrine causes of HTN, the most frequent is primary aldosteronism (PA), which also is the most frequent cause of secondary HTN and could represent 10% of all HTN patients. Cushing syndrome and pheochromocytoma and paraganglioma (PPGL) are rarer (less than 0.5% of patients). In this review, among endocrine causes of HTN, we will mainly discuss explorations for PA and PPGL. |
format | Online Article Text |
id | pubmed-8780426 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87804262022-01-22 How to Explore an Endocrine Cause of Hypertension de Freminville, Jean-Baptiste Amar, Laurence J Clin Med Review Hypertension (HTN) is the most frequent modifiable risk factor in the world, affecting almost 30 to 40% of the adult population in the world. Among hypertensive patients, 10 to 15% have so-called “secondary” HTN, which means HTN due to an identified cause. The most frequent secondary causes of HTN are renal arteries abnormalities (renovascular HTN), kidney disease, and endocrine HTN, which are primarily due to adrenal causes. Knowing how to detect and explore endocrine causes of hypertension is particularly interesting because some causes have a cure or a specific treatment available. Moreover, the delayed diagnosis of secondary HTN is a major cause of uncontrolled blood pressure. Therefore, screening and exploration of patients at risk for secondary HTN should be a serious concern for every physician seeing patients with HTN. Regarding endocrine causes of HTN, the most frequent is primary aldosteronism (PA), which also is the most frequent cause of secondary HTN and could represent 10% of all HTN patients. Cushing syndrome and pheochromocytoma and paraganglioma (PPGL) are rarer (less than 0.5% of patients). In this review, among endocrine causes of HTN, we will mainly discuss explorations for PA and PPGL. MDPI 2022-01-14 /pmc/articles/PMC8780426/ /pubmed/35054115 http://dx.doi.org/10.3390/jcm11020420 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review de Freminville, Jean-Baptiste Amar, Laurence How to Explore an Endocrine Cause of Hypertension |
title | How to Explore an Endocrine Cause of Hypertension |
title_full | How to Explore an Endocrine Cause of Hypertension |
title_fullStr | How to Explore an Endocrine Cause of Hypertension |
title_full_unstemmed | How to Explore an Endocrine Cause of Hypertension |
title_short | How to Explore an Endocrine Cause of Hypertension |
title_sort | how to explore an endocrine cause of hypertension |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780426/ https://www.ncbi.nlm.nih.gov/pubmed/35054115 http://dx.doi.org/10.3390/jcm11020420 |
work_keys_str_mv | AT defreminvillejeanbaptiste howtoexploreanendocrinecauseofhypertension AT amarlaurence howtoexploreanendocrinecauseofhypertension |