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Antidepressant Sertraline Is a Broad-Spectrum Inhibitor of Enteroviruses Targeting Viral Entry through Neutralization of Endolysosomal Acidification

Enterovirus 71 (EV71) is an etiological agent of hand foot and mouth disease and can also cause neurological complications in young children. However, there are no approved drugs as of yet to treat EV71 infections. In this study, we conducted antiviral drug screening by using a Food and Drug Adminis...

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Detalles Bibliográficos
Autores principales: Tseng, Kuan-Chi, Hsu, Bang-Yan, Ling, Pin, Lu, Wen-Wen, Lin, Cheng-Wen, Kung, Szu-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780434/
https://www.ncbi.nlm.nih.gov/pubmed/35062313
http://dx.doi.org/10.3390/v14010109