Biphasic Functions of Sodium Fluoride (NaF) in Soft and in Hard Periodontal Tissues

Sodium fluoride (NaF) is widely used in clinical dentistry. However, the administration of high or low concentrations of NaF has various functions in different tissues. Understanding the mechanisms of the different effects of NaF will help to optimize its use in clinical applications. Studies of NaF...

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Detalles Bibliográficos
Autores principales: Wang, Xingzhi, Tewari, Nitesh, Sato, Fuyuki, Tanimoto, Keiji, Thangavelu, Lakshmi, Makishima, Makoto, Bhawal, Ujjal K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780524/
https://www.ncbi.nlm.nih.gov/pubmed/35055148
http://dx.doi.org/10.3390/ijms23020962
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author Wang, Xingzhi
Tewari, Nitesh
Sato, Fuyuki
Tanimoto, Keiji
Thangavelu, Lakshmi
Makishima, Makoto
Bhawal, Ujjal K.
author_facet Wang, Xingzhi
Tewari, Nitesh
Sato, Fuyuki
Tanimoto, Keiji
Thangavelu, Lakshmi
Makishima, Makoto
Bhawal, Ujjal K.
author_sort Wang, Xingzhi
collection PubMed
description Sodium fluoride (NaF) is widely used in clinical dentistry. However, the administration of high or low concentrations of NaF has various functions in different tissues. Understanding the mechanisms of the different effects of NaF will help to optimize its use in clinical applications. Studies of NaF and epithelial cells, osteoblasts, osteoclasts, and periodontal cells have suggested the significant roles of fluoride treatment. In this review, we summarize recent studies on the biphasic functions of NaF that are related to both soft and hard periodontal tissues, multiple diseases, and clinical dentistry.
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spelling pubmed-87805242022-01-22 Biphasic Functions of Sodium Fluoride (NaF) in Soft and in Hard Periodontal Tissues Wang, Xingzhi Tewari, Nitesh Sato, Fuyuki Tanimoto, Keiji Thangavelu, Lakshmi Makishima, Makoto Bhawal, Ujjal K. Int J Mol Sci Review Sodium fluoride (NaF) is widely used in clinical dentistry. However, the administration of high or low concentrations of NaF has various functions in different tissues. Understanding the mechanisms of the different effects of NaF will help to optimize its use in clinical applications. Studies of NaF and epithelial cells, osteoblasts, osteoclasts, and periodontal cells have suggested the significant roles of fluoride treatment. In this review, we summarize recent studies on the biphasic functions of NaF that are related to both soft and hard periodontal tissues, multiple diseases, and clinical dentistry. MDPI 2022-01-16 /pmc/articles/PMC8780524/ /pubmed/35055148 http://dx.doi.org/10.3390/ijms23020962 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Wang, Xingzhi
Tewari, Nitesh
Sato, Fuyuki
Tanimoto, Keiji
Thangavelu, Lakshmi
Makishima, Makoto
Bhawal, Ujjal K.
Biphasic Functions of Sodium Fluoride (NaF) in Soft and in Hard Periodontal Tissues
title Biphasic Functions of Sodium Fluoride (NaF) in Soft and in Hard Periodontal Tissues
title_full Biphasic Functions of Sodium Fluoride (NaF) in Soft and in Hard Periodontal Tissues
title_fullStr Biphasic Functions of Sodium Fluoride (NaF) in Soft and in Hard Periodontal Tissues
title_full_unstemmed Biphasic Functions of Sodium Fluoride (NaF) in Soft and in Hard Periodontal Tissues
title_short Biphasic Functions of Sodium Fluoride (NaF) in Soft and in Hard Periodontal Tissues
title_sort biphasic functions of sodium fluoride (naf) in soft and in hard periodontal tissues
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780524/
https://www.ncbi.nlm.nih.gov/pubmed/35055148
http://dx.doi.org/10.3390/ijms23020962
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