The Neuroactive Steroid Pregnanolone Glutamate: Anticonvulsant Effect, Metabolites and Its Effect on Neurosteroid Levels in Developing Rat Brains

Pregnanolone glutamate (PA-G) is a neuroactive steroid that has been previously demonstrated to be a potent neuroprotective compound in several biological models in vivo. Our in vitro experiments identified PA-G as an inhibitor of N-methyl-D-aspartate receptors and a potentiator of γ-aminobutyric ac...

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Detalles Bibliográficos
Autores principales: Kudova, Eva, Mares, Pavel, Hill, Martin, Vondrakova, Katerina, Tsenov, Grygoriy, Chodounska, Hana, Kubova, Hana, Vales, Karel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780580/
https://www.ncbi.nlm.nih.gov/pubmed/35056106
http://dx.doi.org/10.3390/ph15010049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780580/
https://www.ncbi.nlm.nih.gov/pubmed/35056106
http://dx.doi.org/10.3390/ph15010049

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