Cargando…

Pharmacokinetics and Metabolism Study of Deep-Sea-Derived Butyrolactone I in Rats by UHPLC–MS/MS and UHPLC–Q-TOF-MS

Butyrolactone I (BTL-I) is a butanolide isolated from the deep-sea-derived fungus, Aspergillus sp. It provides a potential new target for the prevention and treatment of food allergies. This study aimed to investigate the metabolic and pharmacokinetic profile of BTL-I in rats. The metabolic profiles...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Liang, Xie, Chun-Lan, Yang, Xian-Wen, Chen, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780701/ https://www.ncbi.nlm.nih.gov/pubmed/35049869 http://dx.doi.org/10.3390/md20010011

Ejemplares similares

Identification and Pharmacokinetic Studies on Complanatuside and Its Major Metabolites in Rats by UHPLC-Q-TOF-MS/MS and LC-MS/MS
por: Yao, Yu-Feng, et al.
Publicado: (2018)

Metabolic profiling and pharmacokinetic studies of Baihu-Guizhi decoction in rats by UFLC-Q-TOF–MS/MS and UHPLC-Q-TRAP-MS/MS
por: He, Yan, et al.
Publicado: (2022)

Identification for metabolism profiles and pharmacokinetic studies of tradition Chinese prescription Ji-Ming-San and its major metabolites in rats by UHPLC-Q-TOF-MS/MS and UHPLC-MS/MS
por: Hsieh, Cheng-Yang, et al.
Publicado: (2023)

Pharmacokinetics and Metabolism Research of Shenkang Injection in Rats Based on UHPLC-MS/MS and UHPLC-Q-Orbitrap HRMS
por: Jiang, Xiaofang, et al.
Publicado: (2020)

Identification of Metabolites of Eupatorin in Vivo and in Vitro Based on UHPLC-Q-TOF-MS/MS
por: Li, Luya, et al.
Publicado: (2019)

Dynamic profiling of intact glucosinolates in radish by combining UHPLC-HRMS/MS and UHPLC-QqQ-MS/MS
por: Yan, Chenghuan, et al.
Publicado: (2023)

UHPLC‐Q‐TOF‐MS/MS Dereplication to Identify Chemical Constituents of Hedera helix Leaves in Vietnam
por: Pham, Hong Ngoc, et al.
Publicado: (2022)

Determination of Alkaloids and Flavonoids in Sophora flavescens by UHPLC-Q-TOF/MS
por: Dong, Yaqian, et al.
Publicado: (2021)

On-line identification of the chemical constituents of Polygoni Multiflori Radix by UHPLC-Q-ToF MS/MS
por: Wang, Xueting, et al.
Publicado: (2023)

Study on Pharmacokinetics and Metabolic Profiles of Novel Potential PLK-1 Inhibitors by UHPLC-MS/MS Combined with UHPLC-Q-Orbitrap/HRMS
por: Wang, Lin, et al.
Publicado: (2023)

Rapid Identification of Berberine Metabolites in Rat Plasma by UHPLC-Q-TOF-MS
por: Xu, Peng, et al.
Publicado: (2019)

Metabolite Profiling of Meridianin C In Vivo of Rat by UHPLC/Q-TOF MS
por: Zhang, Guozhe, et al.
Publicado: (2021)

Screening and Identification of the Main Metabolites of Schisantherin a In Vivo and In Vitro by Using UHPLC-Q-TOF-MS/MS
por: Feng, Wei, et al.
Publicado: (2020)

Metabolite Identification of Isopropoxy Benzene Guanidine in Rat Liver Microsomes by Using UHPLC-Q-TOF-MS/MS
por: Lu, Yixing, et al.
Publicado: (2023)

Extraction Optimization, UHPLC-Triple-TOF-MS/MS Analysis and Antioxidant Activity of Ceramides from Sea Red Rice Bran
por: Wang, Gang, et al.
Publicado: (2022)

Stereoselective pharmacokinetic study of epiprogoitrin and progoitrin in rats with UHPLC–MS/MS method
por: Xu, Yan, et al.
Publicado: (2020)

RNA-Seq and UHPLC-Q-TOF/MS Based Lipidomics Study in Lysiphlebia japonica
por: Gao, Xueke, et al.
Publicado: (2018)

Analysis of In Vivo Existence Forms of Nardosinone in Mice by UHPLC-Q-TOF-MS Technique
por: Zhang, Jing, et al.
Publicado: (2022)

Untargeted Metabolomics of Fermented Rice Using UHPLC Q-TOF MS/MS Reveals an Abundance of Potential Antihypertensive Compounds
por: Daliri, Eric Banan-Mwine, et al.
Publicado: (2020)

Identification of metabolites of liquiritin in rats by UHPLC-Q-TOF-MS/MS: metabolic profiling and pathway comparison in vitro and in vivo
por: Zhang, Xia, et al.
Publicado: (2018)

A comprehensive study of eriocitrin metabolism in vivo and in vitro based on an efficient UHPLC-Q-TOF-MS/MS strategy
por: Li, Luya, et al.
Publicado: (2019)

A Study of the Identification, Fragmentation Mode and Metabolic Pathways of Imatinib in Rats Using UHPLC-Q-TOF-MS/MS
por: Liu, Sijiang, et al.
Publicado: (2021)

Anticonvulsant Activity of Bombyx batryticatus and Analysis of Bioactive Extracts Based on UHPLC-Q-TOF MS/MS and Molecular Networking
por: Wang, Qinglei, et al.
Publicado: (2022)

UHPLC-Q-TOF-MS/MS-oriented characteristic components dataset and multivariate statistical techniques for the holistic quality control of Usnea
por: Jin, Yiran, et al.
Publicado: (2018)

Analysis of isoquinoline alkaloids from Mahonia leschenaultia and Mahonia napaulensis roots using UHPLC-Orbitrap-MS(n) and UHPLC-QqQ(LIT)-MS/MS
por: Singh, Awantika, et al.
Publicado: (2017)

Pharmacokinetic Study and Metabolite Identification of CAM106 in Rats by Validated UHPLC-MS/MS
por: Xi, Ruqi, et al.
Publicado: (2023)

Chemical Discrimination of Astragalus mongholicus and Astragalus membranaceus Based on Metabolomics Using UHPLC-ESI-Q-TOF-MS/MS Approach
por: Wang, Yumei, et al.
Publicado: (2019)

UHPLC-Q-TOF-MS/MS and Network Pharmacology Analysis to Reveal Quality Markers of Xinjiang Cydonia oblonga Mill. for Antiatherosclerosis
por: Simayi, Jimilihan, et al.
Publicado: (2022)

Screening of metabolic markers present in Oxytropis by UHPLC-Q-TOF/MS and preliminary pharmacophylogenetic investigation
por: Jia, Xin, et al.
Publicado: (2022)

Comparison of Two Methods, UHPLC-UV and UHPLC-MS/MS, for the Quantification of Polyphenols in Cider Apple Juices
por: Verdu, Cindy F., et al.
Publicado: (2013)

Studies on the metabolism and degradation of vancomycin in simulated in vitro and aquatic environment by UHPLC-Triple-TOF-MS/MS
por: Cao, Mengsi, et al.
Publicado: (2018)

Quantitative Lipidomic Analysis of Osteosarcoma Cell-Derived Products by UHPLC-MS/MS
por: Casati, Sara, et al.
Publicado: (2020)

Determination of iohexol by capillary blood microsampling and UHPLC-MS/MS
por: Ion, Valentin, et al.
Publicado: (2019)

Determination of Paraquat in Arabidopsis Tissues and Protoplasts by UHPLC-MS/MS
por: Zhao, Mingming, et al.
Publicado: (2023)

Quantification of rutin in rat's brain by UHPLC/ESI-Q-TOF-MS/MS after intranasal administration of rutin loaded chitosan nanoparticles
por: Ahmad, Niyaz, et al.
Publicado: (2016)

Isolation and Identification of the Anti-Oxidant Constituents from Loropetalum chinense (R. Brown) Oliv. Based on UHPLC–Q-TOF-MS/MS
por: Chen, Haifang, et al.
Publicado: (2018)

UHPLC-ESI-Q-TOF-MS/MS analysis, antioxidant activity combined fingerprints for quality consistency evaluation of compound liquorice tablets
por: Zhang, Yujing, et al.
Publicado: (2018)

Simultaneous Determination of Structurally Diverse Compounds in Different Fangchi Species by UHPLC-DAD and UHPLC-ESI-MS/MS
por: Sim, Hee-Jung, et al.
Publicado: (2013)

Evaluation of the Effect of Eslicarbazepine Acetate on the Pharmacokinetics of Perampanel in Rats by Isotope-Dilution-UHPLC-MS/MS
por: Liu, Ping, et al.
Publicado: (2022)

UHPLC-MS/MS metabolomics analysis of sea cucumber (Apostichopus japonicus) processed using different methods
por: Zhang, Jinyuan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_o7iplje0ge0s3ls3fpivnklqov