Cargando…

HIV-1 Nef Protein Affects Cytokine and Extracellular Vesicles Production in the GEN2.2 Plasmacytoid Dendritic Cell Line

Plasmacytoid dendritic cells (pDCs) are a unique dendritic cell subset specialized in type I interferon production, whose role in Human Immunodeficiency Virus (HIV) infection and pathogenesis is complex and not yet well defined. Considering the crucial role of the accessory protein Nef in HIV pathog...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aiello, Alessandra, Giannessi, Flavia, Percario, Zulema Antonia, Fecchi, Katia, Arenaccio, Claudia, Leone, Stefano, Carollo, Maria, D’Aversa, Elisabetta, Chaperot, Laurence, Gambari, Roberto, Sargiacomo, Massimo, Affabris, Elisabetta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780779/ https://www.ncbi.nlm.nih.gov/pubmed/35062278 http://dx.doi.org/10.3390/v14010074

Ejemplares similares

The Role of Extracellular Vesicles as Allies of HIV, HCV and SARS Viruses
por: Giannessi, Flavia, et al.
Publicado: (2020)

SARS-CoV-2 Evasion of the Interferon System: Can We Restore Its Effectiveness?
por: Sacchi, Alessandra, et al.
Publicado: (2023)

HIV-1 Myristoylated Nef Treatment of Murine Microglial Cells Activates Inducible Nitric Oxide Synthase, NO(2) Production and Neurotoxic Activity
por: Mangino, Giorgio, et al.
Publicado: (2015)

HIV-1 Nef Induces Proinflammatory State in Macrophages through Its Acidic Cluster Domain: Involvement of TNF Alpha Receptor Associated Factor 2
por: Mangino, Giorgio, et al.
Publicado: (2011)

HMGB1 and Cord Blood: Its Role as Immuno-Adjuvant Factor in Innate Immunity
por: Ciucci, Alessandra, et al.
Publicado: (2011)

In vitro induction of interleukin-8 by SARS-CoV-2 Spike protein is inhibited in bronchial epithelial IB3-1 cells by a miR-93-5p agomiR
por: Gasparello, Jessica, et al.
Publicado: (2021)

Sulforaphane inhibits the expression of interleukin-6 and interleukin-8 induced in bronchial epithelial IB3-1 cells by exposure to the SARS-CoV-2 Spike protein
por: Gasparello, Jessica, et al.
Publicado: (2021)

Non-invasive fetal sex diagnosis in plasma of early weeks pregnants using droplet digital PCR
por: D’Aversa, Elisabetta, et al.
Publicado: (2018)

Interferon-β Induces Cellular Senescence in Cutaneous Human Papilloma Virus-Transformed Human Keratinocytes by Affecting p53 Transactivating Activity
por: Chiantore, Maria V., et al.
Publicado: (2012)

N-Terminal Fatty Acids of NEF(MUT) Are Required for the CD8(+) T-Cell Immunogenicity of In Vivo Engineered Extracellular Vesicles
por: Chiozzini, Chiara, et al.
Publicado: (2020)

A novel intracellular antibody against the E6 oncoprotein impairs growth of human papillomavirus 16-positive tumor cells in mouse models
por: Amici, Carla, et al.
Publicado: (2016)

UPF1 silenced cellular model systems for screening of read-through agents active on β(0)39 thalassemia point mutation
por: Salvatori, Francesca, et al.
Publicado: (2018)

Postnatal and non-invasive prenatal detection of β-thalassemia mutations based on Taqman genotyping assays
por: Breveglieri, Giulia, et al.
Publicado: (2017)

Detection of the sickle hemoglobin allele using a surface plasmon resonance based biosensor
por: Breveglieri, Giulia, et al.
Publicado: (2019)

Inhibition by Thyroid Hormones of Cell Migration Activated by IGF-1 and MCP-1 in THP-1 Monocytes: Focus on Signal Transduction Events Proximal to Integrin αvβ3
por: Candelotti, Elena, et al.
Publicado: (2021)

Efficient Delivery of MicroRNA and AntimiRNA Molecules Using an Argininocalix[4]arene Macrocycle
por: Gasparello, Jessica, et al.
Publicado: (2019)

Cell Propagation of Cholera Toxin CTA ADP-Ribosylating Factor by Exosome Mediated Transfer
por: Zanetti, Cristiana, et al.
Publicado: (2018)

Droplet Digital PCR for Non-Invasive Prenatal Detection of Fetal Single-Gene Point Mutations in Maternal Plasma
por: D’Aversa, Elisabetta, et al.
Publicado: (2022)

Characterization of species-specific genes regulated by E2-2 in human plasmacytoid dendritic cells
por: Cheng, Menglan, et al.
Publicado: (2015)

The Intracellular Delivery Of Anti-HPV16 E7 scFvs Through Engineered Extracellular Vesicles Inhibits The Proliferation Of HPV-Infected Cells
por: Ferrantelli, Flavia, et al.
Publicado: (2019)

HIV-1 Nef Impairs Key Functional Activities in Human Macrophages through CD36 Downregulation
por: Olivetta, Eleonora, et al.
Publicado: (2014)

Thyroid Hormones Interaction With Immune Response, Inflammation and Non-thyroidal Illness Syndrome
por: De Luca, Roberto, et al.
Publicado: (2021)

Screening Readthrough Compounds to Suppress Nonsense Mutations: Possible Application to β-Thalassemia
por: Borgatti, Monica, et al.
Publicado: (2020)

Caveolin-1 Endows Order in Cholesterol-Rich Detergent Resistant Membranes
por: Raggi, Carla, et al.
Publicado: (2019)

Extranuclear effects of thyroid hormones and analogs during development: An old mechanism with emerging roles
por: Incerpi, Sandra, et al.
Publicado: (2022)

Discovery of Novel Fetal Hemoglobin Inducers through Small Chemical Library Screening
por: Breveglieri, Giulia, et al.
Publicado: (2020)

Staphylococcus aureus Esx Factors Control Human Dendritic Cell Functions Conditioning Th1/Th17 Response
por: Cruciani, Melania, et al.
Publicado: (2017)

P16-52. HIV-activated human plasmacytoid DCs induce Tregs through an indoleamine 2,3-dioxygenase-dependent mechanism
por: Manches, O, et al.
Publicado: (2009)

Effects of Sirolimus treatment on patients with β‐Thalassemia: Lymphocyte immunophenotype and biological activity of memory CD4 (+) and CD8 (+) T cells
por: Zurlo, Matteo, et al.
Publicado: (2023)

Highly efficient transduction of human plasmacytoid dendritic cells without phenotypic and functional maturation
por: Veron, Philippe, et al.
Publicado: (2009)

Plasmacytoid Dendritic Cells Capture and Cross-Present Viral Antigens from Influenza-Virus Exposed Cells
por: Lui, Gabrielle, et al.
Publicado: (2009)

The MEK1/2-ERK Pathway Inhibits Type I IFN Production in Plasmacytoid Dendritic Cells
por: Janovec, Vaclav, et al.
Publicado: (2018)

Purification and Characterization of Antibodies in Single-Chain Format against the E6 Oncoprotein of Human Papillomavirus Type 16
por: Verachi, F., et al.
Publicado: (2018)

Acidic microenvironment plays a key role in human melanoma progression through a sustained exosome mediated transfer of clinically relevant metastatic molecules
por: Boussadia, Zaira, et al.
Publicado: (2018)

A Novel Cancer Vaccine Strategy Based on HLA-A*0201 Matched Allogeneic Plasmacytoid Dendritic Cells
por: Aspord, Caroline, et al.
Publicado: (2010)

Coronavirus Interplay With Lipid Rafts and Autophagy Unveils Promising Therapeutic Targets
por: Fecchi, Katia, et al.
Publicado: (2020)

Potent Bidirectional Cross-Talk Between Plasmacytoid Dendritic Cells and γδT Cells Through BTN3A, Type I/II IFNs and Immune Checkpoints
por: Girard, Pauline, et al.
Publicado: (2020)

Add-on-LUCAS2™-Reanimation am NEF Innsbruck
por: Schwaiger, D., et al.
Publicado: (2022)

miRNAs Epigenetic Tuning of Wall Remodeling in the Early Phase after Myocardial Infarction: A Novel Epidrug Approach
por: Salvatori, Francesca, et al.
Publicado: (2023)

Tetherin/BST-2 Antagonism by Nef Depends on a Direct Physical Interaction between Nef and Tetherin, and on Clathrin-mediated Endocytosis
por: Serra-Moreno, Ruth, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_d03gv0houosoif1oeiobs6u8om