HiPSC-Derived Hepatocyte-like Cells Can Be Used as a Model for Transcriptomics-Based Study of Chemical Toxicity

Traditional toxicity risk assessment approaches have until recently focussed mainly on histochemical readouts for cell death. Modern toxicology methods attempt to deduce a mechanistic understanding of pathways involved in the development of toxicity, by using transcriptomics and other big data-drive...

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Detalles Bibliográficos
Autores principales: Ghosh, Sreya, De Smedt, Jonathan, Tricot, Tine, Proença, Susana, Kumar, Manoj, Nami, Fatemeharefeh, Vanwelden, Thomas, Vidal, Niels, Jennings, Paul, Kramer, Nynke I., Verfaillie, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780865/
https://www.ncbi.nlm.nih.gov/pubmed/35051043
http://dx.doi.org/10.3390/toxics10010001

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