YTHDF1 promotes mRNA degradation via YTHDF1‐AGO2 interaction and phase separation

OBJECTIVES: YTHDF1 is known as a m(6)A reader protein, and many researches of YTHDF1 focused on the regulation of mRNA translation efficiency. However, YTHDF1 is also related to RNA degradation, but how YTHDF1 regulates mRNA degradation is indefinite. Liquid‐liquid phase separation (LLPS) underlies...

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Detalles Bibliográficos
Autores principales: Li, Jiong, Chen, Ke, Dong, Xin, Xu, Yating, Sun, Qi, Wang, Honghong, Chen, Zhen, Liu, Cong, Liu, Rong, Yang, Zhe, Mei, Xiangfei, Zhang, Rongyu, Chang, Liuping, Tian, Zongwen, Chen, Jianjun, Liang, Kaiwei, He, Chunjiang, Luo, Mengcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780909/
https://www.ncbi.nlm.nih.gov/pubmed/34821414
http://dx.doi.org/10.1111/cpr.13157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780909/
https://www.ncbi.nlm.nih.gov/pubmed/34821414
http://dx.doi.org/10.1111/cpr.13157

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