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Substrate stiffness regulates the differentiation profile and functions of osteoclasts via cytoskeletal arrangement

OBJECTIVES: Aging and common diseases alter the stiffness of bone tissue, causing changes to the microenvironment of the mechanosensitive bone cells. Osteoclasts, the sole bone‐resorbing cells, play a vital role in bone remodeling. This study was performed to elucidate the mechanism through which os...

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Detalles Bibliográficos
Autores principales: Wang, Qingxuan, Xie, Jing, Zhou, Chenchen, Lai, Wenli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780927/
https://www.ncbi.nlm.nih.gov/pubmed/34953003
http://dx.doi.org/10.1111/cpr.13172