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Engineering human skin model innervated with itch sensory neuron‐like cells differentiated from induced pluripotent stem cells

Atopic dermatitis (AD), driven by interleukins (IL‐4/IL‐13), is a chronic inflammatory skin disease characterized by intensive pruritus. However, it is unclear how immune signaling and sensory response pathways cross talk with each other. We differentiated itch sensory neuron‐like cells (ISNLCs) fro...

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Detalles Bibliográficos
Autores principales: Guo, Zongyou, Tong, Chi‐Kun, Jacków, Joanna, Doucet, Yanne S., Abaci, Hasan E., Zeng, Wangyong, Hansen, Corey, Hayashi, Ryota, DeLorenzo, Dominick, Rami, Avina, Pappalardo, Alberto, Lumpkin, Ellen A., Christiano, Angela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780951/
https://www.ncbi.nlm.nih.gov/pubmed/35111948
http://dx.doi.org/10.1002/btm2.10247