Cargando…

Ibogaine Has Sex-Specific Plasma Bioavailability, Histopathological and Redox/Antioxidant Effects in Rat Liver and Kidneys: A Study on Females

Ibogaine induces rapid changes in cellular energetics followed by the elevation of antioxidant activities. As shown earlier in male rats, ibogaine treatment with both 1 and 20 mg/kg b.w. per os led to significant glycogenolytic activity in the liver. In this work, female rats treated with the same d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tatalović, Nikola, Vidonja Uzelac, Teodora, Mijović, Milica, Koželj, Gordana, Nikolić-Kokić, Aleksandra, Oreščanin Dušić, Zorana, Bresjanac, Mara, Blagojević, Duško
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780973/ https://www.ncbi.nlm.nih.gov/pubmed/35054409 http://dx.doi.org/10.3390/life12010016

Ejemplares similares

Ibogaine-Mediated ROS/Antioxidant Elevation in Isolated Rat Uterus Is β-Adrenergic Receptors and K(ATP) Channels Mediated
por: Tatalović, Nikola, et al.
Publicado: (2021)

The Effects of Ibogaine on Uterine Smooth Muscle Contractions: Relation to the Activity of Antioxidant Enzymes
por: Oreščanin-Dušić, Zorana, et al.
Publicado: (2018)

Antipsychotic Drug-Mediated Adverse Effects on Rat Testicles May Be Caused by Altered Redox and Hormonal Homeostasis
por: Nikolić-Kokić, Aleksandra, et al.
Publicado: (2022)

Reversible Oxidation of Myometrial Voltage-Gated Potassium Channels with Hydrogen Peroxide
por: Appiah, Isabella, et al.
Publicado: (2012)

The humanised CYP2C19 transgenic mouse exhibits cerebellar atrophy and movement impairment reminiscent of ataxia
por: Milosavljević, Filip, et al.
Publicado: (2023)

N-(Hydroxymethyl)ibogaine
por: Jarraya, Raoudha Mezghani, et al.
Publicado: (2008)

Cardiac arrest after ibogaine intoxication
por: Steinberg, Christian, et al.
Publicado: (2018)

Effects of Fructose and Stress on Rat Renal Copper Metabolism and Antioxidant Enzymes Function
por: Tasić, Danica, et al.
Publicado: (2022)

The Mechanistic Basis for Noncompetitive Ibogaine Inhibition of Serotonin and Dopamine Transporters
por: Bulling, Simon, et al.
Publicado: (2012)

The Anti-Addiction Drug Ibogaine and the Heart: A Delicate Relation
por: Koenig, Xaver, et al.
Publicado: (2015)

Ibogaine and addiction in the animal model, a systematic review and meta-analysis
por: Belgers, M, et al.
Publicado: (2016)

Ibogaine microdosing in a patient with bipolar depression: a case report
por: Fernandes-Nascimento, Maria Helha, et al.
Publicado: (2022)

“Herbal seizures” – atypical symptoms after ibogaine intoxication: a case report
por: Breuer, Lorenz, et al.
Publicado: (2015)

Morphing of Ibogaine: A Successful Attempt into the Search for Sigma-2 Receptor Ligands
por: Floresta, Giuseppe, et al.
Publicado: (2019)

Tropane-Based Ibogaine Analog Rescues Folding-Deficient Serotonin and Dopamine Transporters
por: Bhat, Shreyas, et al.
Publicado: (2020)

Acclimations to Cold and Warm Conditions Differently Affect the Energy Metabolism of Diapausing Larvae of the European Corn Borer Ostrinia nubilalis (Hbn.)
por: Popović, Željko D., et al.
Publicado: (2021)

Ibogaine Blocks Cue- and Drug-Induced Reinstatement of Conditioned Place Preference to Ethanol in Male Mice
por: Henriques, Gabrielle M., et al.
Publicado: (2021)

The anti-addictive drug ibogaine modulates voltage-gated ion channels and may trigger cardiac arrhythmias
por: Kovar, Michael, et al.
Publicado: (2011)

Ibogaine Detoxification Transitions Opioid and Cocaine Abusers Between Dependence and Abstinence: Clinical Observations and Treatment Outcomes
por: Mash, Deborah C., et al.
Publicado: (2018)

Ibogaine Administration Modifies GDNF and BDNF Expression in Brain Regions Involved in Mesocorticolimbic and Nigral Dopaminergic Circuits
por: Marton, Soledad, et al.
Publicado: (2019)

Ibogaine modulates cocaine responses which are altered due to environmental habituation: In vivo microvoltammetric and behavioral studies()
por: Broderick, Patricia A., et al.
Publicado: (1994)

Safety of ibogaine administration in detoxification of opioid‐dependent individuals: a descriptive open‐label observational study
por: Knuijver, Thomas, et al.
Publicado: (2021)

A nationwide assessment of the burden of healthcare-associated infections and antimicrobial use among surgical patients: results from Serbian point prevalence survey, 2017
por: Šuljagić, Vesna, et al.
Publicado: (2021)

Thermal (In)stability of Atropine and Scopolamine in the GC-MS Inlet
por: Koželj, Gordana, et al.
Publicado: (2021)

The anti-addiction drug ibogaine inhibits cardiac ion channels: a study to assess the drug’s proarrhythmic potential
por: Koenig, Xaver, et al.
Publicado: (2012)

Subjective effectiveness of ibogaine treatment for problematic opioid consumption: Short- and long-term outcomes and current psychological functioning
por: DAVIS, ALAN K., et al.
Publicado: (2017)

Anti-addiction Drug Ibogaine Prolongs the Action Potential in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
por: Rubi, Lena, et al.
Publicado: (2016)

Effect of Cold Acclimation on Selected Metabolic Enzymes During Diapause in The European Corn Borer Ostrinia nubilalis (Hbn.)
por: Uzelac, Iva, et al.
Publicado: (2020)

Ibogaine Acute Administration in Rats Promotes Wakefulness, Long-Lasting REM Sleep Suppression, and a Distinctive Motor Profile
por: González, Joaquín, et al.
Publicado: (2018)

Case report: Ibogaine reduced severe neuropathic pain associated with a case of brachial plexus nerve root avulsion
por: Dickinson, Jonathan E., et al.
Publicado: (2023)

Plasma levels of an atropine/scopolamine mixture following ingestion of low doses as food contaminant
por: Perharič, Lucija, et al.
Publicado: (2012)

Cytochrome P450 and O-methyltransferase catalyze the final steps in the biosynthesis of the anti-addictive alkaloid ibogaine from Tabernanthe iboga
por: Farrow, Scott C., et al.
Publicado: (2018)

The Influence of Extracellular Superoxide on Iron Redox Chemistry and Bioavailability to Aquatic Microorganisms
por: Rose, Andrew L.
Publicado: (2012)

Anti-addiction drug ibogaine inhibits voltage-gated ionic currents: A study to assess the drug's cardiac ion channel profile()
por: Koenig, Xaver, et al.
Publicado: (2013)

Long-Term Effects of Maternal Deprivation on Redox Regulation in Rat Brain: Involvement of NADPH Oxidase
por: Marković, Branka, et al.
Publicado: (2017)

Effect of Spray Drying Encapsulation on Nettle Leaf Extract Powder Properties, Polyphenols and Their Bioavailability
por: Cegledi, Ena, et al.
Publicado: (2022)

Aging diminishes the resistance of AO rats to EAE: putative role of enhanced generation of GM-CSF Expressing CD4+ T cells in aged rats
por: Stojić-Vukanić, Zorica, et al.
Publicado: (2015)

Role of the Encapsulation in Bioavailability of Phenolic Compounds
por: Grgić, Josipa, et al.
Publicado: (2020)

Rare tradition of the folk medicinal use of Aconitum spp. is kept alive in Solčavsko, Slovenia
por: Povšnar, Marija, et al.
Publicado: (2017)

The Effect of a High-Protein Diet Supplemented with Blackthorn Flower Extract on Polyphenol Bioavailability and Antioxidant Status in the Organs of C57BL/6 Mice
por: Balta, Vedran, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_09g6crpmfh8o7fou2uk8tfhpma