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The Chimeric Binjari-Zika Vaccine Provides Long-Term Protection against ZIKA Virus Challenge

We recently developed a chimeric flavivirus vaccine technology based on the novel insect-specific Binjari virus (BinJV) and used this to generate a chimeric ZIKV vaccine (BinJ/ZIKA-prME) that protected IFNAR(-/-) dams and fetuses from infection. Herein, we show that a single vaccination of IFNAR(-/-...

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Detalles Bibliográficos
Autores principales: Hazlewood, Jessamine E., Tang, Bing, Yan, Kexin, Rawle, Daniel J., Harrison, Jessica J., Hall, Roy A., Hobson-Peters, Jody, Suhrbier, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781009/
https://www.ncbi.nlm.nih.gov/pubmed/35062746
http://dx.doi.org/10.3390/vaccines10010085