Different pancreatic cancer microenvironments convert iPSCs into cancer stem cells exhibiting distinct plasticity with altered gene expression of metabolic pathways

BACKGROUND: Cancer stem cells (CSCs) are generated under irregular microenvironment in vivo, of which mimic is quite difficult due to the lack of enough information of the factors responsible for cancer initiation. Here, we demonstrated that mouse induced pluripotent cells (miPSCs) reprogrammed from...

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Detalles Bibliográficos
Autores principales: Hassan, Ghmkin, Ohara, Toshiaki, Afify, Said M., Kumon, Kazuki, Zahra, Maram H., Fu, Xiaoying, Al Kadi, Mohamad, Seno, Akimasa, Salomon, David S., Seno, Masaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781112/
https://www.ncbi.nlm.nih.gov/pubmed/35063003
http://dx.doi.org/10.1186/s13046-021-02167-3

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