Lethal and Sub-Lethal Effects and Modulation of Gene Expression Induced by T Kinase Inhibitors in Zebrafish (Danio Rerio) Embryos

Tyrosine kinase inhibitors (TKIs) are designed for targeted cancer therapy. The consumption of these drugs during the last 20 years has been constantly rising. In the zebrafish (Danio rerio) embryo toxicity test, we assessed the toxicity of six TKIs: imatinib mesylate, erlotinib, nilotinib, dasatini...

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Detalles Bibliográficos
Autores principales: Elersek, Tina, Novak, Matjaž, Mlinar, Mateja, Virant, Igor, Bahor, Nika, Leben, Karin, Žegura, Bojana, Filipič, Metka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781212/
https://www.ncbi.nlm.nih.gov/pubmed/35051046
http://dx.doi.org/10.3390/toxics10010004

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