Cargando…

Bioinformatics analysis and identification of hub genes and immune-related molecular mechanisms in chronic myeloid leukemia

BACKGROUND: Chronic myeloid leukemia (CML) is a malignant hyperplastic tumor of the bone marrow originating from pluripotent hematopoietic stem cells. The advent of tyrosine kinase inhibitors (TKIs) has greatly improved the survival rate of patients with CML. However, TKI-resistance leads to the dis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yao, Fangyi, Zhao, Cui, Zhong, Fangmin, Qin, Tingyu, Li, Shuqi, Liu, Jing, Huang, Bo, Wang, Xiaozhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2022
Materias:	Bioinformatics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781323/ https://www.ncbi.nlm.nih.gov/pubmed/35111390 http://dx.doi.org/10.7717/peerj.12616

Ejemplares similares

Identification of hub genes and potential molecular mechanisms in gastric cancer by integrated bioinformatics analysis
por: Cao, Ling, et al.
Publicado: (2018)

Identification of hub genes and small-molecule compounds related to intracerebral hemorrhage with bioinformatics analysis
por: Liu, Zhendong, et al.
Publicado: (2019)

Integrated bioinformatics analysis for the identification of hub genes and signaling pathways related to circANRIL
por: Qin, Qiuyan, et al.
Publicado: (2022)

m6A-related lncRNAs predict prognosis and indicate immune microenvironment in acute myeloid leukemia
por: Zhong, Fangmin, et al.
Publicado: (2022)

Identification and validation of hub genes involved in foam cell formation and atherosclerosis development via bioinformatics
por: Teng, Da, et al.
Publicado: (2023)

Identification of hub genes and biological pathways in hepatocellular carcinoma by integrated bioinformatics analysis
por: Zhao, Qian, et al.
Publicado: (2021)

Significance of hub genes and immune cell infiltration identified by bioinformatics analysis in pelvic organ prolapse
por: Zhao, Ying, et al.
Publicado: (2020)

Identification of the hub gene BUB1B in hepatocellular carcinoma via bioinformatic analysis and in vitro experiments
por: Fu, Jie, et al.
Publicado: (2021)

Inflammatory response mediates cross-talk with immune function and reveals clinical features in acute myeloid leukemia
por: Zhong, Fang-Min, et al.
Publicado: (2022)

ceRNA network construction and identification of hub genes as novel therapeutic targets for age-related cataracts using bioinformatics
por: Hong, Yingying, et al.
Publicado: (2023)

Identification of four hub genes associated with adrenocortical carcinoma progression by WGCNA
por: Xia, Wang-Xiao, et al.
Publicado: (2019)

Identification of hub genes related to prognosis in glioma
por: Zhang, Delong, et al.
Publicado: (2020)

Identifying hub genes of papillary thyroid carcinoma in the TCGA and GEO database using bioinformatics analysis
por: Wan, Ying, et al.
Publicado: (2020)

Immune‐relatedlncRNAs can predict the prognosis of acute myeloid leukemia
por: Li, Ran, et al.
Publicado: (2021)

Identification of hub genes associated with the pathogenesis of diffuse large B-cell lymphoma subtype one characterized by host response via integrated bioinformatic analyses
por: Zhou, Lingna, et al.
Publicado: (2020)

Identification of key biomarkers and immune infiltration in the synovial tissue of osteoarthritis by bioinformatics analysis
por: Cai, Weisong, et al.
Publicado: (2020)

Identification of the hub genes and pathways involved in acute myeloid leukemia using bioinformatics analysis
por: Tan, Youping, et al.
Publicado: (2020)

Reduced expression of lncRNA DLEU7-AS1 is a novel favorable prognostic factor in acute myeloid leukemia
por: Wang, Cui-zhu, et al.
Publicado: (2022)

Identification of dysregulated genes in rheumatoid arthritis based on bioinformatics analysis
por: Hao, Ruihu, et al.
Publicado: (2017)

Identification of cellular senescence-related signature for predicting prognosis and therapeutic response of acute myeloid leukemia
por: Zhong, Fangmin, et al.
Publicado: (2023)

Identification of key modules and hub genes associated with lung function in idiopathic pulmonary fibrosis
por: Xia, Yuechong, et al.
Publicado: (2020)

Identification of immune related cells and crucial genes in the peripheral blood of ankylosing spondylitis by integrated bioinformatics analysis
por: Zheng, Yang, et al.
Publicado: (2021)

Identification of immune-related genes in acute myocardial infarction based on integrated bioinformatical methods and experimental verification
por: Liu, Jian, et al.
Publicado: (2023)

Identification of the hub genes in gastric cancer through weighted gene co-expression network analysis
por: Li, Chunyang, et al.
Publicado: (2021)

Integrated analysis reveals distinct molecular, clinical, and immunological features of B7‐H3 in acute myeloid leukemia
por: Zhang, Ling‐yi, et al.
Publicado: (2021)

The m(6)A regulator KIAA1429 stabilizes RAB27B mRNA and promotes the progression of chronic myeloid leukemia and resistance to targeted therapy
por: Yao, Fangyi, et al.
Publicado: (2023)

Comprehensive analysis of abnormal expression, prognostic value and oncogenic role of the hub gene FN1 in pancreatic ductal adenocarcinoma via bioinformatic analysis and in vitro experiments
por: Lei, Xiaohua, et al.
Publicado: (2021)

Bioinformatic analysis and identification of potential prognostic microRNAs and mRNAs in thyroid cancer
por: Tang, Jianing, et al.
Publicado: (2018)

Identification of significant genes signatures and prognostic biomarkers in cervical squamous carcinoma via bioinformatic data
por: He, Yunan, et al.
Publicado: (2020)

Identification of key gene modules and hub genes of human mantle cell lymphoma by coexpression network analysis
por: Guo, Dongmei, et al.
Publicado: (2020)

Novel lncRNAs with diagnostic or prognostic value screened out from breast cancer via bioinformatics analyses
por: Wang, Hongxian, et al.
Publicado: (2022)

Clinical and prognostic relevance of CXCL12 expression in acute myeloid leukemia
por: Wang, Shi-sen, et al.
Publicado: (2021)

Bioinformatic pipelines for whole transcriptome sequencing data exploitation in leukemia patients with complex structural variants
por: Hynst, Jakub, et al.
Publicado: (2019)

Identification of CDT1 as a prognostic marker in human lung adenocarcinoma using bioinformatics approaches
por: Jiang, Jing, et al.
Publicado: (2023)

Identification of Flap endonuclease 1 as a potential core gene in hepatocellular carcinoma by integrated bioinformatics analysis
por: Li, Chuanfei, et al.
Publicado: (2019)

Identification of an immune prognostic 11-gene signature for lung adenocarcinoma
por: Yang, Tao, et al.
Publicado: (2021)

Identification of prognostic risk factors for pancreatic cancer using bioinformatics analysis
por: Jin, Dandan, et al.
Publicado: (2020)

Identification of potential gene signatures associated with osteosarcoma by integrated bioinformatics analysis
por: Jia, Yutao, et al.
Publicado: (2021)

Bioinformatic prediction of the molecular links between Alzheimer’s disease and diabetes mellitus
por: Castillo-Velázquez, Ricardo, et al.
Publicado: (2023)

Identification of hub genes and transcription factor-miRNA-mRNA pathways in mice and human renal ischemia-reperfusion injury
por: Ke, Peng, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_81gv4h7je0uhb0srd1t9kopgho