Lack of Support for the Genes by Early Environment Interaction Hypothesis in the Pathogenesis of Schizophrenia

Ursini et al reported recently that the liability of schizophrenia explained by a polygenic risk score (PRS) derived from the variants most associated with schizophrenia was increased 5-fold in individuals who experienced complications during pregnancy or birth. Follow-up gene expression analysis sh...

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Detalles Bibliográficos
Autores principales: Vassos, Evangelos, Kou, Jiaqi, Tosato, Sarah, Maxwell, Jessye, Dennison, Charlotte A, Legge, Sophie E, Walters, James T R, Owen, Michael J, O’Donovan, Michael C, Breen, Gerome, Lewis, Cathryn M, Sullivan, Patrick F, Hultman, Christina, Ruggeri, Mirella, Walshe, Muriel, Bramon, Elvira, Bergen, Sarah E, Murray, Robin M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Regular Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781344/
https://www.ncbi.nlm.nih.gov/pubmed/33987677
http://dx.doi.org/10.1093/schbul/sbab052

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