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Derivation and Molecular Characterization of a Morphological Subpopulation of Human iPSC Astrocytes Reveal a Potential Role in Schizophrenia and Clozapine Response

Astrocytes are the most abundant cell type in the human brain and are important regulators of several critical cellular functions, including synaptic transmission. Although astrocytes are known to play a central role in the etiology and pathophysiology of schizophrenia, little is known about their p...

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Detalles Bibliográficos
Autores principales: Akkouh, Ibrahim A, Hribkova, Hana, Grabiec, Marta, Budinska, Eva, Szabo, Attila, Kasparek, Tomas, Andreassen, Ole A, Sun, Yuh-Man, Djurovic, Srdjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781347/
https://www.ncbi.nlm.nih.gov/pubmed/34357384
http://dx.doi.org/10.1093/schbul/sbab092