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New IMB16-4 Nanoparticles Improved Oral Bioavailability and Enhanced Anti-Hepatic Fibrosis on Rats
Liver fibrosis is challenging to treat because of the lack of effective agents worldwide. Recently, we have developed a novel compound, N-(3,4,5-trichlorophenyl)-2(3-nitrobenzenesulfonamido) benzamide referred to as IMB16-4. However, its poor aqueous solubility and poor oral bioavailability obstruct...
Autores principales: | Niu, Xia, Wang, Xiaomei, Niu, Bingyu, Wang, Yucheng, He, Hongwei, Li, Guiling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781400/ https://www.ncbi.nlm.nih.gov/pubmed/35056142 http://dx.doi.org/10.3390/ph15010085 |
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