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Met-RANTES preserves the blood–brain barrier through inhibiting CCR1/SRC/Rac1 pathway after intracerebral hemorrhage in mice

BACKGROUND: C–C chemokine receptor type 1 (CCR1) and its endogenous ligand, CCL5, participate in the pathogenesis of neuroinflammatory diseases. However, much remains unknown regarding CCL5/CCR1 signaling in blood–brain barrier (BBB) permeability after intracerebral hemorrhage (ICH). METHODS: A tota...

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Detalles Bibliográficos
Autores principales:	Yan, Jun, Xu, Weilin, Lenahan, Cameron, Huang, Lei, Ocak, Umut, Wen, Jing, Li, Gaigai, He, Wei, Le, Chensheng, Zhang, John H., Mo, Ligen, Tang, Jiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781527/ https://www.ncbi.nlm.nih.gov/pubmed/35062973 http://dx.doi.org/10.1186/s12987-022-00305-3

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