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Design of Bio-Responsive Hyaluronic Acid–Doxorubicin Conjugates for the Local Treatment of Glioblastoma
Glioblastoma is an unmet clinical need. Local treatment strategies offer advantages, such as the possibility to bypass the blood–brain barrier, achieving high drug concentrations at the glioblastoma site, and consequently reducing systemic toxicity. In this study, we evaluated the feasibility of usi...
Autores principales: | Malfanti, Alessio, Catania, Giuseppina, Degros, Quentin, Wang, Mingchao, Bausart, Mathilde, Préat, Véronique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781529/ https://www.ncbi.nlm.nih.gov/pubmed/35057020 http://dx.doi.org/10.3390/pharmaceutics14010124 |
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