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Small Drugs, Huge Impact: The Extraordinary Impact of Antisense Oligonucleotides in Research and Drug Development

Antisense oligonucleotides (ASOs) are an increasingly represented class of drugs. These small sequences of nucleotides are designed to precisely target other oligonucleotides, usually RNA species, and are modified to protect them from degradation by nucleases. Their specificity is due to their seque...

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Detalles Bibliográficos
Autores principales: Quemener, Anais M., Centomo, Maria Laura, Sax, Scott L., Panella, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781596/
https://www.ncbi.nlm.nih.gov/pubmed/35056851
http://dx.doi.org/10.3390/molecules27020536