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Small Drugs, Huge Impact: The Extraordinary Impact of Antisense Oligonucleotides in Research and Drug Development
Antisense oligonucleotides (ASOs) are an increasingly represented class of drugs. These small sequences of nucleotides are designed to precisely target other oligonucleotides, usually RNA species, and are modified to protect them from degradation by nucleases. Their specificity is due to their seque...
Autores principales: | Quemener, Anais M., Centomo, Maria Laura, Sax, Scott L., Panella, Riccardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781596/ https://www.ncbi.nlm.nih.gov/pubmed/35056851 http://dx.doi.org/10.3390/molecules27020536 |
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