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Receptor Specificity Engineering of TNF Superfamily Ligands

The tumor necrosis factor (TNF) ligand family has nine ligands that show promiscuity in binding multiple receptors. As different receptors transduce into diverse pathways, the study on the functional role of natural ligands is very complex. In this review, we discuss the TNF ligands engineering for...

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Detalles Bibliográficos
Autores principales: Suo, Fengzhi, Zhou, Xinyu, Setroikromo, Rita, Quax, Wim J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781899/
https://www.ncbi.nlm.nih.gov/pubmed/35057080
http://dx.doi.org/10.3390/pharmaceutics14010181