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Receptor Specificity Engineering of TNF Superfamily Ligands
The tumor necrosis factor (TNF) ligand family has nine ligands that show promiscuity in binding multiple receptors. As different receptors transduce into diverse pathways, the study on the functional role of natural ligands is very complex. In this review, we discuss the TNF ligands engineering for...
Autores principales: | Suo, Fengzhi, Zhou, Xinyu, Setroikromo, Rita, Quax, Wim J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781899/ https://www.ncbi.nlm.nih.gov/pubmed/35057080 http://dx.doi.org/10.3390/pharmaceutics14010181 |
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