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Oxyresveratrol Inhibits TNF-α-Stimulated Cell Proliferation in Human Immortalized Keratinocytes (HaCaT) by Suppressing AKT Activation

Psoriasis is a complex inflammatory disease characterized by hyperproliferative keratinocyte caused by active PI3K/AKT signaling. TNF-α concentrated in the psoriatic lesions stimulates AKT activation. We previously discovered that oxyresveratrol inhibited inflammation via suppressing AKT phosphoryla...

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Detalles Bibliográficos
Autores principales:	Wikan, Nitwara, Hankittichai, Phateep, Thaklaewphan, Phatarawat, Potikanond, Saranyapin, Nimlamool, Wutigri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781909/ https://www.ncbi.nlm.nih.gov/pubmed/35056961 http://dx.doi.org/10.3390/pharmaceutics14010063

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