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Multicenter Study of Benign Thyroid Nodules with Radiofrequency Ablation: Results of 762 Cases over 4 Years in Taiwan

Background: To evaluate the effectiveness and safety of radiofrequency ablation (RFA) treatment for benign thyroid nodules (BTNs) in five medical centers in Taiwan. Methods: From April 2016 to July 2020, 762 patients underwent ultrasound guided RFA treatment of 826 benign thyroid nodules at five med...

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Autores principales: Lin, Wei-Che, Wang, Cheng-Kang, Wang, Wen-Hung, Kuo, Chi-Yu, Chiang, Pi-Ling, Lin, An-Ni, Baek, Jung Hwan, Wu, Ming-Hsun, Cheng, Kai-Lun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782025/
https://www.ncbi.nlm.nih.gov/pubmed/35055378
http://dx.doi.org/10.3390/jpm12010063
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author Lin, Wei-Che
Wang, Cheng-Kang
Wang, Wen-Hung
Kuo, Chi-Yu
Chiang, Pi-Ling
Lin, An-Ni
Baek, Jung Hwan
Wu, Ming-Hsun
Cheng, Kai-Lun
author_facet Lin, Wei-Che
Wang, Cheng-Kang
Wang, Wen-Hung
Kuo, Chi-Yu
Chiang, Pi-Ling
Lin, An-Ni
Baek, Jung Hwan
Wu, Ming-Hsun
Cheng, Kai-Lun
author_sort Lin, Wei-Che
collection PubMed
description Background: To evaluate the effectiveness and safety of radiofrequency ablation (RFA) treatment for benign thyroid nodules (BTNs) in five medical centers in Taiwan. Methods: From April 2016 to July 2020, 762 patients underwent ultrasound guided RFA treatment of 826 benign thyroid nodules at five medical centers in Taiwan. The RFA procedure was performed by radiologists, otolaryngologists, or surgeons. Patients were grouped into three subgroups according to the initial volume of BTNs. The volume reduction ratio (VRR) of each nodule, and complications were analyzed at 1, 3, and 6 months after RFA treatment and the three groups compared. Results: The large nodular group showed greater VRR compared to the other two groups at first 1-month follow-up. At 6-months follow-up, there was no significant difference of VRR among the three groups. Goiters with difference in size can attain a successful VRR (>50%) although different specialists demonstrated variable VRR after 6-months follow-up. A total of 40 (4.8%) complications were reported. All patients recovered spontaneously without surgery intervention. Conclusions: The reliability and safety of RFA for benign thyroid nodules had been established. RFA has gradually become an alternative to surgery in the treatment of benign thyroid nodules in Taiwan.
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spelling pubmed-87820252022-01-22 Multicenter Study of Benign Thyroid Nodules with Radiofrequency Ablation: Results of 762 Cases over 4 Years in Taiwan Lin, Wei-Che Wang, Cheng-Kang Wang, Wen-Hung Kuo, Chi-Yu Chiang, Pi-Ling Lin, An-Ni Baek, Jung Hwan Wu, Ming-Hsun Cheng, Kai-Lun J Pers Med Article Background: To evaluate the effectiveness and safety of radiofrequency ablation (RFA) treatment for benign thyroid nodules (BTNs) in five medical centers in Taiwan. Methods: From April 2016 to July 2020, 762 patients underwent ultrasound guided RFA treatment of 826 benign thyroid nodules at five medical centers in Taiwan. The RFA procedure was performed by radiologists, otolaryngologists, or surgeons. Patients were grouped into three subgroups according to the initial volume of BTNs. The volume reduction ratio (VRR) of each nodule, and complications were analyzed at 1, 3, and 6 months after RFA treatment and the three groups compared. Results: The large nodular group showed greater VRR compared to the other two groups at first 1-month follow-up. At 6-months follow-up, there was no significant difference of VRR among the three groups. Goiters with difference in size can attain a successful VRR (>50%) although different specialists demonstrated variable VRR after 6-months follow-up. A total of 40 (4.8%) complications were reported. All patients recovered spontaneously without surgery intervention. Conclusions: The reliability and safety of RFA for benign thyroid nodules had been established. RFA has gradually become an alternative to surgery in the treatment of benign thyroid nodules in Taiwan. MDPI 2022-01-06 /pmc/articles/PMC8782025/ /pubmed/35055378 http://dx.doi.org/10.3390/jpm12010063 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lin, Wei-Che
Wang, Cheng-Kang
Wang, Wen-Hung
Kuo, Chi-Yu
Chiang, Pi-Ling
Lin, An-Ni
Baek, Jung Hwan
Wu, Ming-Hsun
Cheng, Kai-Lun
Multicenter Study of Benign Thyroid Nodules with Radiofrequency Ablation: Results of 762 Cases over 4 Years in Taiwan
title Multicenter Study of Benign Thyroid Nodules with Radiofrequency Ablation: Results of 762 Cases over 4 Years in Taiwan
title_full Multicenter Study of Benign Thyroid Nodules with Radiofrequency Ablation: Results of 762 Cases over 4 Years in Taiwan
title_fullStr Multicenter Study of Benign Thyroid Nodules with Radiofrequency Ablation: Results of 762 Cases over 4 Years in Taiwan
title_full_unstemmed Multicenter Study of Benign Thyroid Nodules with Radiofrequency Ablation: Results of 762 Cases over 4 Years in Taiwan
title_short Multicenter Study of Benign Thyroid Nodules with Radiofrequency Ablation: Results of 762 Cases over 4 Years in Taiwan
title_sort multicenter study of benign thyroid nodules with radiofrequency ablation: results of 762 cases over 4 years in taiwan
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782025/
https://www.ncbi.nlm.nih.gov/pubmed/35055378
http://dx.doi.org/10.3390/jpm12010063
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