Cargando…

Molecular Modelling a Key Method for Potential Therapeutic Drug Discovery

The well-defined and characterized 3D crystal structure of a protein is important to explore the topological and physiological features of the protein. The distinguished topography of a protein helps medical chemists design drugs on the basis of the pharmacophoric features of the protein. Structure-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Karkoutly, Omar, Dhasmana, Anupam, Dhevan, Vijian, Chauhan, Subhash C., Tripathi, Manish K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782051/ https://www.ncbi.nlm.nih.gov/pubmed/35071996 http://dx.doi.org/10.26717/BJSTR.2021.37.006000

Ejemplares similares

Boosting Mitochondrial Potential: An Imperative Therapeutic Intervention in Amyotrophic Lateral Sclerosis
por: Dhasmana, Swati, et al.
Publicado: (2023)

Withania somnifera as a potential future drug molecule for COVID-19
por: Kashyap, Vivek K, et al.
Publicado: (2020)

miR-205: A Potential Biomedicine for Cancer Therapy
por: Chauhan, Neeraj, et al.
Publicado: (2020)

Breakthrough medicines during the COVID-19 pandemic era
por: Ghali, Eswara Naga Hanuma Kumar, et al.
Publicado: (2022)

Withania somnifera: Progress towards a Pharmaceutical Agent for Immunomodulation and Cancer Therapeutics
por: Kashyap, Vivek K., et al.
Publicado: (2022)

Role of Nutraceuticals in COVID-19 Mediated Liver Dysfunction
por: Sikander, Mohammed, et al.
Publicado: (2020)

Integrative big transcriptomics data analysis implicates crucial role of MUC13 in pancreatic cancer
por: Dhasmana, Anupam, et al.
Publicado: (2023)

Glutathione-Responsive Tannic Acid-Assisted FRET Nanomedicine for Cancer Therapy
por: Laskar, Partha, et al.
Publicado: (2023)

Topological and system-level protein interaction network (PIN) analyses to deduce molecular mechanism of curcumin
por: Dhasmana, Anupam, et al.
Publicado: (2020)

Stress and Molecular Drivers for Cancer Progression: A Longstanding Hypothesis
por: Wendel, J, et al.
Publicado: (2021)

Key Milestones in HCV Discovery and Therapeutics
por: Cheng, Xiaoming, et al.
Publicado: (2020)

Tannic Acid Exhibits Antiangiogenesis Activity in Nonsmall-Cell Lung Cancer Cells
por: Hatami, Elham, et al.
Publicado: (2022)

Indocyanine Green-based Glow Nanoparticles Probe for Cancer Imaging
por: Chauhan, Neeraj, et al.
Publicado: (2023)

Therapeutic Potential of Plants as Anti-microbials for Drug Discovery
por: Perumal Samy, Ramar, et al.
Publicado: (2010)

Smoking and COVID-19: Adding Fuel to the Flame
por: Kashyap, Vivek K., et al.
Publicado: (2020)

Editorial: Antimycobacterial drug discovery: Molecular therapeutics and target identification
por: Gunosewoyo, Hendra, et al.
Publicado: (2022)

Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods
por: Wu, Canrong, et al.
Publicado: (2020)

Evolving scenario of big data and Artificial Intelligence (AI) in drug discovery
por: Tripathi, Manish Kumar, et al.
Publicado: (2021)

Development and therapeutic potential of 2-aminothiazole derivatives in anticancer drug discovery
por: Alizadeh, Seyedeh Roya, et al.
Publicado: (2021)

Emerging Roles and Potential Applications of Non-Coding RNAs in Cervical Cancer
por: Parashar, Deepak, et al.
Publicado: (2022)

Key drivers of biomedical innovation in cancer drug discovery
por: Huber, Margit A, et al.
Publicado: (2015)

Editorial: Antimycobacterial drug discovery: molecular therapeutics and target identification, Volume II
por: Gunosewoyo, Hendra, et al.
Publicado: (2023)

Molecular Docking of Known Carcinogen 4- (Methyl-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK) with Cyclin Dependent Kinases towards Its Potential Role in Cell Cycle Perturbation
por: Haneef, Mohd, et al.
Publicado: (2014)

Comparative Molecular Docking Studies with ABCC1 and Aquaporin 9 in the Arsenite Complex Efflux
por: Poojan, Shiv, et al.
Publicado: (2014)

Coronaviruses — drug discovery and therapeutic options
por: Zumla, Alimuddin, et al.
Publicado: (2016)

Human coronaviruses and therapeutic drug discovery
por: Song, Lan-Gui, et al.
Publicado: (2021)

Key factors influencing ADME properties of therapeutic proteins: A need for ADME characterization in drug discovery and development
por: Tibbitts, Jay, et al.
Publicado: (2015)

Recent Advances in Molecular Docking for the Research and Discovery of Potential Marine Drugs
por: Chen, Guilin, et al.
Publicado: (2020)

Exploration of potential molecular mechanisms and genotoxicity of anti-cancer drugs using next generation knowledge discovery methods
por: Pushparaj, Peter Natesan, et al.
Publicado: (2023)

Revealing the Therapeutic Uses of Garlic (Allium sativum) and Its Potential for Drug Discovery
por: Tesfaye, Azene
Publicado: (2021)

Computational methods in drug discovery
por: Leelananda, Sumudu P, et al.
Publicado: (2016)

Key Considerations in Targeted Protein Degradation Drug Discovery and Development
por: Qin, Liena, et al.
Publicado: (2022)

Molecular Mechanism of Cancer Susceptibility Associated with Fok1 Single Nucleotide Polymorphism of VDR in Relation to Breast Cancer
por: Raza, Sana, et al.
Publicado: (2019)

COVID-19: inflammatory responses, structure-based drug design and potential therapeutics
por: Tripathi, Neetu, et al.
Publicado: (2021)

Targeting Nucleotide Binding Domain of Multidrug Resistance-associated Protein-1 (MRP1) for the Reversal of Multi Drug Resistance in Cancer
por: Dhasmana, Divya, et al.
Publicado: (2018)

Discovery and therapeutic potential of drugs that shift energy metabolism from mitochondrial respiration to glycolysis
por: Gohil, Vishal M., et al.
Publicado: (2010)

Molecular dynamics simulations and drug discovery
por: Durrant, Jacob D, et al.
Publicado: (2011)

Molecular Pathology in Drug Discovery and Development
por: Tworkoski, Kathryn
Publicado: (2010)

Repurposing of FDA-approved drugs as potential inhibitors of the SARS-CoV-2 main protease: Molecular insights into improved therapeutic discovery
por: Ray, Abhik Kumar, et al.
Publicado: (2022)

The genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discovery
por: Laing, Roz, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_8tnj6hbp6r7a31kea0mh5vb3ee