Stress and Molecular Drivers for Cancer Progression: A Longstanding Hypothesis

Stress management is becoming very important part of cancer patient care. Chronic stressors lead to boost tumorigenesis and promote cancer development, recurrence, and drug resistant leading to poor health outcomes. The Hypothalamic-Pituitary-Adrenal (HPA) axis, which is activated by stress, also re...

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Autores principales: Wendel, J, Verma, A, Dhevan, V, Chauhan, SC, Tripathi, MK
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782052/
https://www.ncbi.nlm.nih.gov/pubmed/35071995
http://dx.doi.org/10.26717/bjstr.2021.37.005953
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author Wendel, J
Verma, A
Dhevan, V
Chauhan, SC
Tripathi, MK
author_facet Wendel, J
Verma, A
Dhevan, V
Chauhan, SC
Tripathi, MK
author_sort Wendel, J
collection PubMed
description Stress management is becoming very important part of cancer patient care. Chronic stressors lead to boost tumorigenesis and promote cancer development, recurrence, and drug resistant leading to poor health outcomes. The Hypothalamic-Pituitary-Adrenal (HPA) axis, which is activated by stress, also regulates Hypothalamic-Pituitary-Thyroid (HPT) axis. Stress related changes in immune function and inflammatory response also leads to reduced immune surveillance resulting in tumorigenesis. This article explores the hormonal axis impacted by stress and how chronic stress can lead to poor outcome of a cancer patient.
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spelling pubmed-87820522022-07-12 Stress and Molecular Drivers for Cancer Progression: A Longstanding Hypothesis Wendel, J Verma, A Dhevan, V Chauhan, SC Tripathi, MK Biomed J Sci Tech Res Article Stress management is becoming very important part of cancer patient care. Chronic stressors lead to boost tumorigenesis and promote cancer development, recurrence, and drug resistant leading to poor health outcomes. The Hypothalamic-Pituitary-Adrenal (HPA) axis, which is activated by stress, also regulates Hypothalamic-Pituitary-Thyroid (HPT) axis. Stress related changes in immune function and inflammatory response also leads to reduced immune surveillance resulting in tumorigenesis. This article explores the hormonal axis impacted by stress and how chronic stress can lead to poor outcome of a cancer patient. 2021-07 2021-07-12 /pmc/articles/PMC8782052/ /pubmed/35071995 http://dx.doi.org/10.26717/bjstr.2021.37.005953 Text en https://creativecommons.org/licenses/by/4.0/This work is licensed under Creative Commons Attribution 4.0 License
spellingShingle Article
Wendel, J
Verma, A
Dhevan, V
Chauhan, SC
Tripathi, MK
Stress and Molecular Drivers for Cancer Progression: A Longstanding Hypothesis
title Stress and Molecular Drivers for Cancer Progression: A Longstanding Hypothesis
title_full Stress and Molecular Drivers for Cancer Progression: A Longstanding Hypothesis
title_fullStr Stress and Molecular Drivers for Cancer Progression: A Longstanding Hypothesis
title_full_unstemmed Stress and Molecular Drivers for Cancer Progression: A Longstanding Hypothesis
title_short Stress and Molecular Drivers for Cancer Progression: A Longstanding Hypothesis
title_sort stress and molecular drivers for cancer progression: a longstanding hypothesis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782052/
https://www.ncbi.nlm.nih.gov/pubmed/35071995
http://dx.doi.org/10.26717/bjstr.2021.37.005953
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