Synthesis and characterization of novel ssDNA X-aptamers targeting Growth Hormone Releasing Hormone (GHRH)

BACKGROUND: Growth Hormone Releasing Hormone (GHRH), 44 amino acids containing hypothalamic hormone, retains the biological activity by its first 29 amino acids. GHRH (NH2 1–29) peptide antagonists inhibit the growth of prostate, breast, ovarian, renal, gastric, pancreatic cancer in vitro and in viv...

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Detalles Bibliográficos
Autores principales: Ayhan-Sahin, Burcu, Apaydın, Zeynep-Elif, Obakan-Yerlikaya, Pınar, Arisan, Elif-Damla, Coker-Gurkan, Ajda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782341/
https://www.ncbi.nlm.nih.gov/pubmed/35061691
http://dx.doi.org/10.1371/journal.pone.0260144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782341/
https://www.ncbi.nlm.nih.gov/pubmed/35061691
http://dx.doi.org/10.1371/journal.pone.0260144

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