MOP and NOP receptor interaction: Studies with a dual expression system and bivalent peptide ligands

Opioids targeting mu;μ (MOP) receptors produce analgesia in the peri-operative period and palliative care. They also produce side effects including respiratory depression, tolerance/dependence and addiction. The N/OFQ opioid receptor (NOP) also produces analgesia but is devoid of the major MOP side...

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Detalles Bibliográficos
Autores principales: Bird, M. F., McDonald, J., Horley, B., O’Doherty, J. P., Fraser, B., Gibson, C. L., Guerrini, R., Caló, G., Lambert, D. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782398/
https://www.ncbi.nlm.nih.gov/pubmed/35061679
http://dx.doi.org/10.1371/journal.pone.0260880

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