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Antimicrobial Usage and Resistance in Makkah Region Hospitals: A Regional Point Prevalence Survey of Public Hospitals
(1) Background: Inappropriate use of antimicrobials and subsequently rise of antimicrobial resistance (AMR) remains a major public health priority. Over-prescribing of broad-spectrum antibiotics is one of the main contributing factors for the emergence of AMR. We sought to describe antimicrobial pre...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782433/ https://www.ncbi.nlm.nih.gov/pubmed/35010512 http://dx.doi.org/10.3390/ijerph19010254 |
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author | Haseeb, Abdul Faidah, Hani Saleh Algethamy, Manal Alghamdi, Saleh Alhazmi, Ghaidaa Ali Alshomrani, Afnan Owedah Alqethami, Bashair Rjyan Alotibi, Hind Saeed Almutiri, Maali Zayed Almuqati, Khawlah Saad Albishi, Amjad Abdullah Elrggal, Mahmoud Essam Mahrous, Ahmad Jamal Khogeer, Asim Abdulaziz Saleem, Zikria Iqbal, Muhammad Shahid Sheikh, Aziz |
author_facet | Haseeb, Abdul Faidah, Hani Saleh Algethamy, Manal Alghamdi, Saleh Alhazmi, Ghaidaa Ali Alshomrani, Afnan Owedah Alqethami, Bashair Rjyan Alotibi, Hind Saeed Almutiri, Maali Zayed Almuqati, Khawlah Saad Albishi, Amjad Abdullah Elrggal, Mahmoud Essam Mahrous, Ahmad Jamal Khogeer, Asim Abdulaziz Saleem, Zikria Iqbal, Muhammad Shahid Sheikh, Aziz |
author_sort | Haseeb, Abdul |
collection | PubMed |
description | (1) Background: Inappropriate use of antimicrobials and subsequently rise of antimicrobial resistance (AMR) remains a major public health priority. Over-prescribing of broad-spectrum antibiotics is one of the main contributing factors for the emergence of AMR. We sought to describe antimicrobial prescribing trends among patients in public hospitals in Makkah hospitals. (2) Method: We undertook a point prevalence survey (PPS) in six hospitals in Makkah, Saudi Arabia, from January 2019 to July 2019. The survey included all the inpatients receiving antimicrobials on the day of PPS. Data was collected using the Global point prevalence survey (PPS) tool developed by the University of Antwerp, Belgium. (3) Results: Of 710 hospitalized patients, 447 patients (61.9%) were treated with one or more antimicrobials during the study period. The average bed occupancy among six hospitals was 74.4%. The majority of patients received antimicrobials parenterally (90.3%). Of the total prescribed antimicrobials, 415 (53.7%) antimicrobials were used in medical departments, 183 (23.7%) in surgical departments, and 175 (22.6%) in ICUs. Pneumonia (17.3%), skin and soft tissue infections (10.9%), and sepsis (6.6.%) were three common clinical indications. Ceftriaxones were the most commonly used antibiotics that were prescribed in 116 (15%) of patients, followed by piperacillin, with an enzyme inhibitor in 84 (10.9%). (4) Conclusion: There was a high prevalence of antibiotic use in the hospitals of Makkah, which could be a potential risk factor for the incidence of resistant strains, particularly MRSA infection. Public health decision-makers should take these findings into consideration to update national policies for antibiotic use in order to reduce the risks of further increases of AMR. |
format | Online Article Text |
id | pubmed-8782433 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87824332022-01-22 Antimicrobial Usage and Resistance in Makkah Region Hospitals: A Regional Point Prevalence Survey of Public Hospitals Haseeb, Abdul Faidah, Hani Saleh Algethamy, Manal Alghamdi, Saleh Alhazmi, Ghaidaa Ali Alshomrani, Afnan Owedah Alqethami, Bashair Rjyan Alotibi, Hind Saeed Almutiri, Maali Zayed Almuqati, Khawlah Saad Albishi, Amjad Abdullah Elrggal, Mahmoud Essam Mahrous, Ahmad Jamal Khogeer, Asim Abdulaziz Saleem, Zikria Iqbal, Muhammad Shahid Sheikh, Aziz Int J Environ Res Public Health Article (1) Background: Inappropriate use of antimicrobials and subsequently rise of antimicrobial resistance (AMR) remains a major public health priority. Over-prescribing of broad-spectrum antibiotics is one of the main contributing factors for the emergence of AMR. We sought to describe antimicrobial prescribing trends among patients in public hospitals in Makkah hospitals. (2) Method: We undertook a point prevalence survey (PPS) in six hospitals in Makkah, Saudi Arabia, from January 2019 to July 2019. The survey included all the inpatients receiving antimicrobials on the day of PPS. Data was collected using the Global point prevalence survey (PPS) tool developed by the University of Antwerp, Belgium. (3) Results: Of 710 hospitalized patients, 447 patients (61.9%) were treated with one or more antimicrobials during the study period. The average bed occupancy among six hospitals was 74.4%. The majority of patients received antimicrobials parenterally (90.3%). Of the total prescribed antimicrobials, 415 (53.7%) antimicrobials were used in medical departments, 183 (23.7%) in surgical departments, and 175 (22.6%) in ICUs. Pneumonia (17.3%), skin and soft tissue infections (10.9%), and sepsis (6.6.%) were three common clinical indications. Ceftriaxones were the most commonly used antibiotics that were prescribed in 116 (15%) of patients, followed by piperacillin, with an enzyme inhibitor in 84 (10.9%). (4) Conclusion: There was a high prevalence of antibiotic use in the hospitals of Makkah, which could be a potential risk factor for the incidence of resistant strains, particularly MRSA infection. Public health decision-makers should take these findings into consideration to update national policies for antibiotic use in order to reduce the risks of further increases of AMR. MDPI 2021-12-27 /pmc/articles/PMC8782433/ /pubmed/35010512 http://dx.doi.org/10.3390/ijerph19010254 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Haseeb, Abdul Faidah, Hani Saleh Algethamy, Manal Alghamdi, Saleh Alhazmi, Ghaidaa Ali Alshomrani, Afnan Owedah Alqethami, Bashair Rjyan Alotibi, Hind Saeed Almutiri, Maali Zayed Almuqati, Khawlah Saad Albishi, Amjad Abdullah Elrggal, Mahmoud Essam Mahrous, Ahmad Jamal Khogeer, Asim Abdulaziz Saleem, Zikria Iqbal, Muhammad Shahid Sheikh, Aziz Antimicrobial Usage and Resistance in Makkah Region Hospitals: A Regional Point Prevalence Survey of Public Hospitals |
title | Antimicrobial Usage and Resistance in Makkah Region Hospitals: A Regional Point Prevalence Survey of Public Hospitals |
title_full | Antimicrobial Usage and Resistance in Makkah Region Hospitals: A Regional Point Prevalence Survey of Public Hospitals |
title_fullStr | Antimicrobial Usage and Resistance in Makkah Region Hospitals: A Regional Point Prevalence Survey of Public Hospitals |
title_full_unstemmed | Antimicrobial Usage and Resistance in Makkah Region Hospitals: A Regional Point Prevalence Survey of Public Hospitals |
title_short | Antimicrobial Usage and Resistance in Makkah Region Hospitals: A Regional Point Prevalence Survey of Public Hospitals |
title_sort | antimicrobial usage and resistance in makkah region hospitals: a regional point prevalence survey of public hospitals |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782433/ https://www.ncbi.nlm.nih.gov/pubmed/35010512 http://dx.doi.org/10.3390/ijerph19010254 |
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