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Antimicrobial Usage and Resistance in Makkah Region Hospitals: A Regional Point Prevalence Survey of Public Hospitals

(1) Background: Inappropriate use of antimicrobials and subsequently rise of antimicrobial resistance (AMR) remains a major public health priority. Over-prescribing of broad-spectrum antibiotics is one of the main contributing factors for the emergence of AMR. We sought to describe antimicrobial pre...

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Autores principales: Haseeb, Abdul, Faidah, Hani Saleh, Algethamy, Manal, Alghamdi, Saleh, Alhazmi, Ghaidaa Ali, Alshomrani, Afnan Owedah, Alqethami, Bashair Rjyan, Alotibi, Hind Saeed, Almutiri, Maali Zayed, Almuqati, Khawlah Saad, Albishi, Amjad Abdullah, Elrggal, Mahmoud Essam, Mahrous, Ahmad Jamal, Khogeer, Asim Abdulaziz, Saleem, Zikria, Iqbal, Muhammad Shahid, Sheikh, Aziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782433/
https://www.ncbi.nlm.nih.gov/pubmed/35010512
http://dx.doi.org/10.3390/ijerph19010254
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author Haseeb, Abdul
Faidah, Hani Saleh
Algethamy, Manal
Alghamdi, Saleh
Alhazmi, Ghaidaa Ali
Alshomrani, Afnan Owedah
Alqethami, Bashair Rjyan
Alotibi, Hind Saeed
Almutiri, Maali Zayed
Almuqati, Khawlah Saad
Albishi, Amjad Abdullah
Elrggal, Mahmoud Essam
Mahrous, Ahmad Jamal
Khogeer, Asim Abdulaziz
Saleem, Zikria
Iqbal, Muhammad Shahid
Sheikh, Aziz
author_facet Haseeb, Abdul
Faidah, Hani Saleh
Algethamy, Manal
Alghamdi, Saleh
Alhazmi, Ghaidaa Ali
Alshomrani, Afnan Owedah
Alqethami, Bashair Rjyan
Alotibi, Hind Saeed
Almutiri, Maali Zayed
Almuqati, Khawlah Saad
Albishi, Amjad Abdullah
Elrggal, Mahmoud Essam
Mahrous, Ahmad Jamal
Khogeer, Asim Abdulaziz
Saleem, Zikria
Iqbal, Muhammad Shahid
Sheikh, Aziz
author_sort Haseeb, Abdul
collection PubMed
description (1) Background: Inappropriate use of antimicrobials and subsequently rise of antimicrobial resistance (AMR) remains a major public health priority. Over-prescribing of broad-spectrum antibiotics is one of the main contributing factors for the emergence of AMR. We sought to describe antimicrobial prescribing trends among patients in public hospitals in Makkah hospitals. (2) Method: We undertook a point prevalence survey (PPS) in six hospitals in Makkah, Saudi Arabia, from January 2019 to July 2019. The survey included all the inpatients receiving antimicrobials on the day of PPS. Data was collected using the Global point prevalence survey (PPS) tool developed by the University of Antwerp, Belgium. (3) Results: Of 710 hospitalized patients, 447 patients (61.9%) were treated with one or more antimicrobials during the study period. The average bed occupancy among six hospitals was 74.4%. The majority of patients received antimicrobials parenterally (90.3%). Of the total prescribed antimicrobials, 415 (53.7%) antimicrobials were used in medical departments, 183 (23.7%) in surgical departments, and 175 (22.6%) in ICUs. Pneumonia (17.3%), skin and soft tissue infections (10.9%), and sepsis (6.6.%) were three common clinical indications. Ceftriaxones were the most commonly used antibiotics that were prescribed in 116 (15%) of patients, followed by piperacillin, with an enzyme inhibitor in 84 (10.9%). (4) Conclusion: There was a high prevalence of antibiotic use in the hospitals of Makkah, which could be a potential risk factor for the incidence of resistant strains, particularly MRSA infection. Public health decision-makers should take these findings into consideration to update national policies for antibiotic use in order to reduce the risks of further increases of AMR.
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spelling pubmed-87824332022-01-22 Antimicrobial Usage and Resistance in Makkah Region Hospitals: A Regional Point Prevalence Survey of Public Hospitals Haseeb, Abdul Faidah, Hani Saleh Algethamy, Manal Alghamdi, Saleh Alhazmi, Ghaidaa Ali Alshomrani, Afnan Owedah Alqethami, Bashair Rjyan Alotibi, Hind Saeed Almutiri, Maali Zayed Almuqati, Khawlah Saad Albishi, Amjad Abdullah Elrggal, Mahmoud Essam Mahrous, Ahmad Jamal Khogeer, Asim Abdulaziz Saleem, Zikria Iqbal, Muhammad Shahid Sheikh, Aziz Int J Environ Res Public Health Article (1) Background: Inappropriate use of antimicrobials and subsequently rise of antimicrobial resistance (AMR) remains a major public health priority. Over-prescribing of broad-spectrum antibiotics is one of the main contributing factors for the emergence of AMR. We sought to describe antimicrobial prescribing trends among patients in public hospitals in Makkah hospitals. (2) Method: We undertook a point prevalence survey (PPS) in six hospitals in Makkah, Saudi Arabia, from January 2019 to July 2019. The survey included all the inpatients receiving antimicrobials on the day of PPS. Data was collected using the Global point prevalence survey (PPS) tool developed by the University of Antwerp, Belgium. (3) Results: Of 710 hospitalized patients, 447 patients (61.9%) were treated with one or more antimicrobials during the study period. The average bed occupancy among six hospitals was 74.4%. The majority of patients received antimicrobials parenterally (90.3%). Of the total prescribed antimicrobials, 415 (53.7%) antimicrobials were used in medical departments, 183 (23.7%) in surgical departments, and 175 (22.6%) in ICUs. Pneumonia (17.3%), skin and soft tissue infections (10.9%), and sepsis (6.6.%) were three common clinical indications. Ceftriaxones were the most commonly used antibiotics that were prescribed in 116 (15%) of patients, followed by piperacillin, with an enzyme inhibitor in 84 (10.9%). (4) Conclusion: There was a high prevalence of antibiotic use in the hospitals of Makkah, which could be a potential risk factor for the incidence of resistant strains, particularly MRSA infection. Public health decision-makers should take these findings into consideration to update national policies for antibiotic use in order to reduce the risks of further increases of AMR. MDPI 2021-12-27 /pmc/articles/PMC8782433/ /pubmed/35010512 http://dx.doi.org/10.3390/ijerph19010254 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Haseeb, Abdul
Faidah, Hani Saleh
Algethamy, Manal
Alghamdi, Saleh
Alhazmi, Ghaidaa Ali
Alshomrani, Afnan Owedah
Alqethami, Bashair Rjyan
Alotibi, Hind Saeed
Almutiri, Maali Zayed
Almuqati, Khawlah Saad
Albishi, Amjad Abdullah
Elrggal, Mahmoud Essam
Mahrous, Ahmad Jamal
Khogeer, Asim Abdulaziz
Saleem, Zikria
Iqbal, Muhammad Shahid
Sheikh, Aziz
Antimicrobial Usage and Resistance in Makkah Region Hospitals: A Regional Point Prevalence Survey of Public Hospitals
title Antimicrobial Usage and Resistance in Makkah Region Hospitals: A Regional Point Prevalence Survey of Public Hospitals
title_full Antimicrobial Usage and Resistance in Makkah Region Hospitals: A Regional Point Prevalence Survey of Public Hospitals
title_fullStr Antimicrobial Usage and Resistance in Makkah Region Hospitals: A Regional Point Prevalence Survey of Public Hospitals
title_full_unstemmed Antimicrobial Usage and Resistance in Makkah Region Hospitals: A Regional Point Prevalence Survey of Public Hospitals
title_short Antimicrobial Usage and Resistance in Makkah Region Hospitals: A Regional Point Prevalence Survey of Public Hospitals
title_sort antimicrobial usage and resistance in makkah region hospitals: a regional point prevalence survey of public hospitals
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782433/
https://www.ncbi.nlm.nih.gov/pubmed/35010512
http://dx.doi.org/10.3390/ijerph19010254
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