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Hyperinflammatory environment drives dysfunctional myeloid cell effector response to bacterial challenge in COVID-19

COVID-19 displays diverse disease severities and symptoms including acute systemic inflammation and hypercytokinemia, with subsequent dysregulation of immune cells. Bacterial superinfections in COVID-19 can further complicate the disease course and are associated with increased mortality. However, t...

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Detalles Bibliográficos
Autores principales: Mairpady Shambat, Srikanth, Gómez-Mejia, Alejandro, Schweizer, Tiziano A., Huemer, Markus, Chang, Chun-Chi, Acevedo, Claudio, Bergada-Pijuan, Judith, Vulin, Clément, Hofmaenner, Daniel A., Scheier, Thomas C., Hertegonne, Sanne, Parietti, Elena, Miroshnikova, Nataliya, Wendel Garcia, Pedro D., Hilty, Matthias P., Buehler, Philipp Karl, Schuepbach, Reto A., Brugger, Silvio D., Zinkernagel, Annelies S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782468/
https://www.ncbi.nlm.nih.gov/pubmed/35007290
http://dx.doi.org/10.1371/journal.ppat.1010176