Pharmacological Blockade of NLRP3 Inflammasome/IL-1β-Positive Loop Mitigates Endothelial Cell Senescence and Dysfunction

The clinical relevance of IL-1β in chronic inflammation underlying atherosclerosis has been reinforced by recent evidence associating pharmacological inhibition of the cytokine with lower cardiovascular risk. Previously, we have demonstrated a direct involvement of IL-1β in endothelial senescence. T...

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Detalles Bibliográficos
Autores principales: Romero, Alejandra, Dongil, Pilar, Valencia, Inés, Vallejo, Susana, Hipólito-Luengo, Álvaro San, Díaz-Araya, Guillermo, Bartha, José L, González-Arlanzón, María M, Rivilla, Fernando, de la Cuesta, Fernando, Sánchez-Ferrer, Carlos F, Peiró, Concepción
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782550/
https://www.ncbi.nlm.nih.gov/pubmed/35111374
http://dx.doi.org/10.14336/AD.2021.0617

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