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Bacterial recognition by PGRP-SA and downstream signalling by Toll/DIF sustain commensal gut bacteria in Drosophila

The gut sets the immune and metabolic parameters for the survival of commensal bacteria. We report that in Drosophila, deficiency in bacterial recognition upstream of Toll/NF-κB signalling resulted in reduced density and diversity of gut bacteria. Translational regulation factor 4E-BP, a transcripti...

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Detalles Bibliográficos
Autores principales: Bahuguna, Shivohum, Atilano, Magda, Glittenberg, Marcus, Lee, Dohun, Arora, Srishti, Wang, Lihui, Zhou, Jun, Redhai, Siamak, Boutros, Michael, Ligoxygakis, Petros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782595/
https://www.ncbi.nlm.nih.gov/pubmed/35007276
http://dx.doi.org/10.1371/journal.pgen.1009992