Marked Elevation of Carcinoembryonic Antigen Without an Identified Primary Gastrointestinal Tumor

Whether profound carcinoembryonic antigen (CEA) elevations, such as > 20 times the upper limit of normal, are of diagnostic use remain unknown. Herein, we present a case of a 55-year-old female with profound serum CEA elevation and multiple pelvic masses but with no evidence of a primary gastroin...

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Detalles Bibliográficos
Autores principales: Salabei, Joshua K, Upadhyay, Dhaval, Haider, Asad, Nanajian, Anthony, Frimer, Leora, Charles, Kipson, Ismail, Zeeshan H, Imboywa, Selina, Khan, Awaad, Louis, Nundia, Iyer, Uma G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782671/
https://www.ncbi.nlm.nih.gov/pubmed/35103194
http://dx.doi.org/10.7759/cureus.20621
Descripción
Sumario:Whether profound carcinoembryonic antigen (CEA) elevations, such as > 20 times the upper limit of normal, are of diagnostic use remain unknown. Herein, we present a case of a 55-year-old female with profound serum CEA elevation and multiple pelvic masses but with no evidence of a primary gastrointestinal tumor following upper endoscopy and colonoscopy. Subsequent immunostaining of resected pelvic masses confirmed adenocarcinoma of colorectal origin. This case report highlights the possible diagnostic role of profound CEA elevation, particularly in cases of unknown primary tumors.

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