Marked Elevation of Carcinoembryonic Antigen Without an Identified Primary Gastrointestinal Tumor

Whether profound carcinoembryonic antigen (CEA) elevations, such as > 20 times the upper limit of normal, are of diagnostic use remain unknown. Herein, we present a case of a 55-year-old female with profound serum CEA elevation and multiple pelvic masses but with no evidence of a primary gastroin...

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Autores principales: Salabei, Joshua K, Upadhyay, Dhaval, Haider, Asad, Nanajian, Anthony, Frimer, Leora, Charles, Kipson, Ismail, Zeeshan H, Imboywa, Selina, Khan, Awaad, Louis, Nundia, Iyer, Uma G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782671/
https://www.ncbi.nlm.nih.gov/pubmed/35103194
http://dx.doi.org/10.7759/cureus.20621
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author Salabei, Joshua K
Upadhyay, Dhaval
Haider, Asad
Nanajian, Anthony
Frimer, Leora
Charles, Kipson
Ismail, Zeeshan H
Imboywa, Selina
Khan, Awaad
Louis, Nundia
Iyer, Uma G
author_facet Salabei, Joshua K
Upadhyay, Dhaval
Haider, Asad
Nanajian, Anthony
Frimer, Leora
Charles, Kipson
Ismail, Zeeshan H
Imboywa, Selina
Khan, Awaad
Louis, Nundia
Iyer, Uma G
author_sort Salabei, Joshua K
collection PubMed
description Whether profound carcinoembryonic antigen (CEA) elevations, such as > 20 times the upper limit of normal, are of diagnostic use remain unknown. Herein, we present a case of a 55-year-old female with profound serum CEA elevation and multiple pelvic masses but with no evidence of a primary gastrointestinal tumor following upper endoscopy and colonoscopy. Subsequent immunostaining of resected pelvic masses confirmed adenocarcinoma of colorectal origin. This case report highlights the possible diagnostic role of profound CEA elevation, particularly in cases of unknown primary tumors.
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spelling pubmed-87826712022-01-30 Marked Elevation of Carcinoembryonic Antigen Without an Identified Primary Gastrointestinal Tumor Salabei, Joshua K Upadhyay, Dhaval Haider, Asad Nanajian, Anthony Frimer, Leora Charles, Kipson Ismail, Zeeshan H Imboywa, Selina Khan, Awaad Louis, Nundia Iyer, Uma G Cureus Internal Medicine Whether profound carcinoembryonic antigen (CEA) elevations, such as > 20 times the upper limit of normal, are of diagnostic use remain unknown. Herein, we present a case of a 55-year-old female with profound serum CEA elevation and multiple pelvic masses but with no evidence of a primary gastrointestinal tumor following upper endoscopy and colonoscopy. Subsequent immunostaining of resected pelvic masses confirmed adenocarcinoma of colorectal origin. This case report highlights the possible diagnostic role of profound CEA elevation, particularly in cases of unknown primary tumors. Cureus 2021-12-22 /pmc/articles/PMC8782671/ /pubmed/35103194 http://dx.doi.org/10.7759/cureus.20621 Text en Copyright © 2021, Salabei et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Salabei, Joshua K
Upadhyay, Dhaval
Haider, Asad
Nanajian, Anthony
Frimer, Leora
Charles, Kipson
Ismail, Zeeshan H
Imboywa, Selina
Khan, Awaad
Louis, Nundia
Iyer, Uma G
Marked Elevation of Carcinoembryonic Antigen Without an Identified Primary Gastrointestinal Tumor
title Marked Elevation of Carcinoembryonic Antigen Without an Identified Primary Gastrointestinal Tumor
title_full Marked Elevation of Carcinoembryonic Antigen Without an Identified Primary Gastrointestinal Tumor
title_fullStr Marked Elevation of Carcinoembryonic Antigen Without an Identified Primary Gastrointestinal Tumor
title_full_unstemmed Marked Elevation of Carcinoembryonic Antigen Without an Identified Primary Gastrointestinal Tumor
title_short Marked Elevation of Carcinoembryonic Antigen Without an Identified Primary Gastrointestinal Tumor
title_sort marked elevation of carcinoembryonic antigen without an identified primary gastrointestinal tumor
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782671/
https://www.ncbi.nlm.nih.gov/pubmed/35103194
http://dx.doi.org/10.7759/cureus.20621
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