Pharmaco-proteogenomic profiling of pediatric diffuse midline glioma to inform future treatment strategies

Diffuse midline glioma (DMG) is a deadly pediatric and adolescent central nervous system (CNS) tumor localized along the midline structures of the brain atop the spinal cord. With a median overall survival (OS) of just 9–11-months, DMG is characterized by global hypomethylation of histone H3 at lysi...

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Detalles Bibliográficos
Autores principales: Findlay, Izac J., De Iuliis, Geoffry N., Duchatel, Ryan J., Jackson, Evangeline R., Vitanza, Nicholas A., Cain, Jason E., Waszak, Sebastian M., Dun, Matthew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782719/
https://www.ncbi.nlm.nih.gov/pubmed/34759345
http://dx.doi.org/10.1038/s41388-021-02102-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782719/
https://www.ncbi.nlm.nih.gov/pubmed/34759345
http://dx.doi.org/10.1038/s41388-021-02102-y

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