Cargando…

Caspase/AIF/apoptosis pathway: a new target of puerarin for diabetes mellitus therapy

Pancreatic β cell damage is one of the crucial factors responsible for the development of type 2 diabetes mellitus (T2DM). Previous studies have suggested that puerarin (PR) could regulate the activities of the mitochondrial respiratory chain complex in diabetic nephropathy (DN); however, whether PR...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liang, Tao, Xu, Xiaohui, Ye, Dongmei, Chen, Wenxia, Gao, Biyun, Huang, Yanjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782775/ https://www.ncbi.nlm.nih.gov/pubmed/31228042 http://dx.doi.org/10.1007/s11033-019-04925-1

Ejemplares similares

OTUD1 Activates Caspase‐Independent and Caspase‐Dependent Apoptosis by Promoting AIF Nuclear Translocation and MCL1 Degradation
por: Luo, Qingyu, et al.
Publicado: (2021)

An AIF orthologue regulates apoptosis in yeast
por: Wissing, Silke, et al.
Publicado: (2004)

Apoptosis-Inducing Factor 2 (AIF-2) Mediates a Caspase-Independent Apoptotic Pathway in the Tropical Sea Cucumber (Holothuria leucospilota)
por: Li, Xiaomin, et al.
Publicado: (2022)

Endonuclease G takes part in AIF-mediated caspase-independent apoptosis in Mycobacterium bovis-infected bovine macrophages
por: Benítez-Guzmán, Alejandro, et al.
Publicado: (2018)

p20BAP31 induces cell apoptosis via both AIF caspase-independent and the ROS/JNK mitochondrial pathway in colorectal cancer
por: Jiang, Xiaohan, et al.
Publicado: (2023)

Puerarin Suppress Apoptosis of Human Osteoblasts via ERK Signaling Pathway
por: Liu, Ling-juan, et al.
Publicado: (2013)

p53- and ROS-mediated AIF pathway involved in TGEV-induced apoptosis
por: DING, Li, et al.
Publicado: (2018)

Expression of AIF and Caspase-3 in New Zealand rabbit with Cervical Spondylosis Myelopathy model
por: Ibrahim, Sabri, et al.
Publicado: (2021)

AKT2 Blocks Nucleus Translocation of Apoptosis-Inducing Factor (AIF) and Endonuclease G (EndoG) While Promoting Caspase Activation during Cardiac Ischemia
por: Yang, Shuai, et al.
Publicado: (2017)

Role of apoptosis-inducing factor (Aif) in the T cell lineage
por: Prabhu, Savit B., et al.
Publicado: (2013)

Metallic nickel nano- and fine particles induce JB6 cell apoptosis through a caspase-8/AIF mediated cytochrome c-independent pathway
por: Zhao, Jinshun, et al.
Publicado: (2009)

Bone morphogenetic protein inhibitors and mitochondria targeting agents synergistically induce apoptosis-inducing factor (AIF) caspase-independent cell death in lung cancer cells
por: Mondal, Arindam, et al.
Publicado: (2022)

Puerarin alleviates the ototoxicity of gentamicin by inhibiting the mitochondria-dependent apoptosis pathway
por: Niu, Ping, et al.
Publicado: (2021)

Glutamate-induced apoptosis in neuronal cells is mediated via caspase-dependent and independent mechanisms involving calpain and caspase-3 proteases as well as apoptosis inducing factor (AIF) and this process is inhibited by equine estrogens
por: Zhang, YueMei, et al.
Publicado: (2006)

The human papillomavirus E6 protein targets apoptosis-inducing factor (AIF) for degradation
por: Shimada, Masaru, et al.
Publicado: (2020)

Puerarin protects renal ischemia-reperfusion injury in rats through NLRP3/Caspase-1/GSDMD pathway
por: Wang, Kangyu, et al.
Publicado: (2023)

Chronopharmacokinetics of Puerarin in Diabetic Rats
por: Zhang, C. T., et al.
Publicado: (2013)

The Effects of Puerarin on Autophagy Through Regulating of the PERK/eIF2α/ATF4 Signaling Pathway Influences Renal Function in Diabetic Nephropathy
por: Xu, Xiaohui, et al.
Publicado: (2020)

Heat Shock Protein 70 Prevents Hyperoxia-Induced Disruption of Lung Endothelial Barrier via Caspase-Dependent and AIF-Dependent Pathways
por: Kondrikov, Dmitry, et al.
Publicado: (2015)

Puerarin in inducing apoptosis of bladder cancer cells through inhibiting SIRT1/p53 pathway
por: Ye, Guomei, et al.
Publicado: (2019)

Prognostic Value of Apoptosis-Inducing Factor (AIF) in Germ Cell Tumors
por: Letkovska, Katarina, et al.
Publicado: (2021)

Synergistic Hypoglycemic Effects of Pumpkin Polysaccharides and Puerarin on Type II Diabetes Mellitus Mice
por: Chen, Xue, et al.
Publicado: (2019)

AIF knockdown induce apoptosis and mitochondrial dysfunction in cochlear spiral ganglion neurons in vitro
por: Zong, Liang, et al.
Publicado: (2020)

Supplementary choline attenuates olive oil lipid emulsion‐induced enterocyte apoptosis through suppression of CELF1/AIF pathway
por: Yan, Jun‐Kai, et al.
Publicado: (2017)

Bnip3 and AIF cooperate to induce apoptosis and cavitation during epithelial morphogenesis
por: Qi, Yanmei, et al.
Publicado: (2012)

Bnip3 and AIF cooperate to induce apoptosis and cavitation during epithelial morphogenesis
por: Qi, Yanmei, et al.
Publicado: (2013)

Apoptosis inducing factor (AIF) mediates lethal redox stress induced by menadione
por: Wiraswati, Hesti Lina, et al.
Publicado: (2016)

Nutrient deprivation induces apoptosis of nucleus pulposus cells via activation of the BNIP3/AIF signalling pathway
por: Liu, Jie, et al.
Publicado: (2017)

Mitochondrial AIF loss causes metabolic reprogramming, caspase-independent cell death blockade, embryonic lethality, and perinatal hydrocephalus
por: Delavallée, Laure, et al.
Publicado: (2020)

Puerarin attenuates the inflammatory response and apoptosis in LPS-stimulated cardiomyocytes
por: YUAN, YUAN, et al.
Publicado: (2016)

Puerarin induces platinum-resistant epithelial ovarian cancer cell apoptosis by targeting SIRT1
por: Duan, Jianxiu, et al.
Publicado: (2021)

Melatonin Protects against Apoptosis-Inducing Factor (AIF)-Dependent Cell Death during Acetaminophen-Induced Acute Liver Failure
por: Liang, Ying-Li, et al.
Publicado: (2012)

TPEN Induces Apoptosis Independently of Zinc Chelator Activity in a Model of Acute Lymphoblastic Leukemia and Ex Vivo Acute Leukemia Cells through Oxidative Stress and Mitochondria Caspase-3- and AIF-Dependent Pathways
por: Mendivil-Perez, Miguel, et al.
Publicado: (2012)

The age-dependent induction of apoptosis-inducing factor (AIF) in the human semitendinosus skeletal muscle
por: Park, Soo Yeon, et al.
Publicado: (2009)

Glabridin triggers over-expression of apoptosis inducing factor (AIF) gene in Candida albicans
por: Moazeni, Maryam, et al.
Publicado: (2018)

A Cell-Permeant Amiloride Derivative Induces Caspase-Independent, AIF-Mediated Programmed Necrotic Death of Breast Cancer Cells
por: Leon, Leonardo J., et al.
Publicado: (2013)

Effects of Puerarin Combined with PLGA/TCP/Puerarin on Osteocalcin and Sialoprotein of Mandibular Defects
por: Guo, Ying, et al.
Publicado: (2022)

Puerarin Attenuates Diabetic Nephropathy by Promoting Autophagy in Podocytes
por: Li, Xueling, et al.
Publicado: (2020)

Molecular Mechanism of Puerarin Against Diabetes and its Complications
por: Bai, Yi-ling, et al.
Publicado: (2022)

Anti-inflammatory activities of puerarin in high-fat diet-fed rats with streptozotocin-induced gestational diabetes mellitus
por: Xu, Wenting, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_52llsrco37qi5laadtjc4sp2lu