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Randomized phase 2 study of perampanel for sporadic amyotrophic lateral sclerosis
OBJECTIVE: To evaluate the efficacy and safety of perampanel in patients with sporadic amyotrophic lateral sclerosis (SALS). METHODS: This randomized, double-blind, placebo-controlled, multicenter, phase 2 clinical study was conducted at 12 sites. Patients with probable or definite ALS as defined by...
Autores principales: | Aizawa, Hitoshi, Kato, Haruhisa, Oba, Koji, Kawahara, Takuya, Okubo, Yoshihiko, Saito, Tomoko, Naito, Makiko, Urushitani, Makoto, Tamaoka, Akira, Nakamagoe, Kiyotaka, Ishii, Kazuhiro, Kanda, Takashi, Katsuno, Masahisa, Atsuta, Naoki, Maeda, Yasushi, Nagai, Makiko, Nishiyama, Kazutoshi, Ishiura, Hiroyuki, Toda, Tatsushi, Kawata, Akihiro, Abe, Koji, Yabe, Ichiro, Takahashi-Iwata, Ikuko, Sasaki, Hidenao, Warita, Hitoshi, Aoki, Masashi, Sobue, Gen, Mizusawa, Hidehiro, Matsuyama, Yutaka, Haga, Tomohiro, Kwak, Shin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782807/ https://www.ncbi.nlm.nih.gov/pubmed/34191081 http://dx.doi.org/10.1007/s00415-021-10670-y |
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